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  1. NHLBI profiles a member of the Foundation’s patient community.

    ... Article Link:  Tenacity Topples Transfusion: How One Woman’s Determination Helped Her Defeat a Devastating Blood Disease Article Source:  ...

    Article last updated 06/13/2016 - 1:51pm.

  2. Blood Transfusions

    Blood Transfusions A transfusion usually involves only certain parts of blood. These might be the red blood cells, platelets or plasma . Rarely ...

    Topic section last updated 03/29/2016 - 7:17pm.

  3. Recent advances in the pathogenesis and treatment of paroxysmal nocturnal hemoglobinuria

    ... PNH were either supportive treatment - often including blood transfusion , anti- thrombosis prophylaxis, and sometimes ...

    Research Article last updated 06/07/2016 - 10:56am.

  4. Polymorphism of the complement receptor 1 gene correlates with hematological response to eculizumab in patients with paroxysmal nocturnal hemoglobinuria

    ... the response is variable and some patients remain red blood cell transfusion -dependent. In 72 patients with hemolytic Paroxysmal Nocturnal ...

    Research Article last updated 09/26/2013 - 3:28pm.

  5. The immunomodulatory agents lenalidomide and thalidomide for treatment of the myelodysplastic syndromes: A clinical practice guideline.

    ... with the aging population. Treatment includes red blood cell transfusion for anemia . The immunomodulatory agents (imids) ...

    Research Article last updated 10/01/2012 - 10:04am.

  6. Personalized medicine for MDS

    ... patients into “lower-risk” disease, where improvement in blood counts is the main goal of therapy, and “higher-risk” disease, where ... agents (ESAs) as a single agent reduces transfusion dependence in about 50% of lower-risk MDS patients.  However, no ...

    Research Review last updated 05/02/2016 - 9:44am.

  7. A randomized phase 3 study of lenalidomide versus placebo in RBC transfusion-dependent patients with Low-/Intermediate-1-risk myelodysplastic syndromes with del5q

    ... Journal Title:  Blood Primary Author:  ... the efficacy and safety of lenalidomide in 205 RBC transfusion-dependent patients with IPSS Low-/Intermediate-1-risk del5q31 ...

    Research Article last updated 07/28/2014 - 9:04am.

  8. First-in Human Clinical Transplant Trial for Severe Aplastic Anemia

    ... There was concurrent interest in using unrelated cord blood transplants and in using half-matched (haploidentical) donors for this ... cord blood stem cells, not the haplo cells. He is currently transfusion independent, has normal blood counts, and with the exception of ...

    Interview last updated 10/04/2017 - 1:36pm.

  9. Blood stream infection after stem cell transplantation in children with idiopathic aplastic anemia

    ... Journal Title:  Biol Blood Marrow Transplant Primary ... transplantation from unrelated donors, frequent blood transfusion before transplantation, major or major+minor mismatch of ABO ...

    Research Article last updated 04/23/2014 - 10:34am.

  10. Variations in erythropoiesis-stimulating agent administration in transfusion-dependent myelodysplastic syndromes impact response

    ... Erythropoiesis-stimulating agents (ESAs) reduce red blood cell (RBC) transfusions in approximately 40% of patients with ... The study cohort consisted of patients with new-onset transfusion dependence (TD). All patients received an ESA at least once during ...

    Research Article last updated 05/26/2015 - 11:49am.