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  1. Reduced Intensity Conditioning in Patients Aged ≤35 With Non-Malignant Disorders Undergoing UCBT, BMT, or PBSCT (RIC HSCT NMD)

    ... (MUD) bone marrow transplant (BMT) or peripheral blood stem cell transplant (PBSCT) in patients with non-malignant disorders ... Blackfan Anemia (DBA) • other congenital transfusion dependent anemias Patients with sickle disease must have one or ...

    Clinical Trial last updated 06/13/2016 - 2:18pm.

  2. Infections in myelodysplastic syndromes: a review

    ... by transiently worsening the pre-existing low white blood cell (WBC) counts. However, this increased risk of infections ... and liver disease and particularly those with greater transfusion needs are most vulnerable to infections. Available data from two ...

    Research Review last updated 05/02/2016 - 9:28am.

  3. Research Retrospective for AA&MDSIF 30th Anniversary - Dr. Neal Young

    ... treating infections, especially fungal infections, excellent blood bank support means that platelets are readily available to most patients, changes in red blood cell transfusion methods have decreased the problem of alloimmunization, and ...

    Interview last updated 05/08/2013 - 2:51pm.

  4. Extended Dosing With Eltrombopag for Severe Aplastic Anemia

    ... Severe aplastic anemia (SAA) is a life-threatening blood disease that can be successfully treated with immunosuppressive drug ... 7 eventually became tri-lineage responders. Nine became transfusion-independent for platelets (median increase in platelet count ...

    Clinical Trial last updated 04/26/2016 - 9:36am.

  5. MDS Drug Therapy

    ... sub-types of MDS Lenalidomide (Revlimid®) for transfusion-dependent MDS patients with isolated del(5q) and with a low or ... had some positive response to treatment, meaning that blood counts went up. The percentage of patients still surviving after two ...

    Topic section last updated 03/10/2016 - 11:26pm.

  6. Nursing Education Modules on MDS Disease Management and Patient Education

    ... – individualized therapy, minimal toxicity, improvement of blood counts, transfusion independence , delay of leukemic transformation, improved ...

    Page last updated 04/27/2015 - 2:44pm.

  7. “Mom, it’s too late. I’m dying.”

    ... Immediately, I got him to the doctor, and he was sent for blood work. He went to his grandmother’s to lay down while I was at work.  ... his blood counts to come back up. Jake continued to be transfusion dependent, and we returned to Boston for another bone marrow ...

    Patient Chronicle last updated 04/26/2016 - 11:43am.

  8. Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

    ... compared to filgrastim (G-CSF) mobilized peripheral blood stem cell (PBSC) transplants, BM allografts have lower CD34+ progenitor ... thrombosis , and/or cytopenia , and/or transfusion dependence and/or recurrent and debilitating hemolytic crisis ...

    Clinical Trial last updated 04/28/2016 - 2:40pm.

  9. Iron Overload and MDS

    ... Anemia , having low number of red blood cells (RBC), affects 80% of patients with MDS, with a substantial ... a short period of time. The amount of iron in a single RBC transfusion is the same as 1,280 cups of cooked spinach. The buildup of iron in ...

    Research Review last updated 05/02/2016 - 9:18am.

  10. HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy (RAFA)

    ... regimen plus a CD34+ selected T-cell depleted peripheral blood stem cell (PBSC) stem cell transplant for the treatment of ... with Fanconi anemia presenting with severe marrow failure (transfusion dependent) or myelodysplastic syndrome, or acute myelogenous ...

    Clinical Trial last updated 04/28/2016 - 8:44am.