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  1. “Mom, it’s too late. I’m dying.”

    ... Immediately, I got him to the doctor, and he was sent for blood work. He went to his grandmother’s to lay down while I was at work.  ... his blood counts to come back up. Jake continued to be transfusion dependent, and we returned to Boston for another bone marrow ...

    Patient Chronicle last updated 04/26/2016 - 11:43am.

  2. Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

    ... compared to filgrastim (G-CSF) mobilized peripheral blood stem cell (PBSC) transplants, BM allografts have lower CD34+ progenitor ... thrombosis , and/or cytopenia , and/or transfusion dependence and/or recurrent and debilitating hemolytic crisis ...

    Clinical Trial last updated 04/28/2016 - 2:40pm.

  3. Medical Resources

    ... an expert to find an answer. Blood and Transplant Information Understanding your ... An international association working to advance transfusion & cellular therapies worldwide. American Red Cross ...

    Page last updated 08/20/2015 - 8:34am.

  4. Iron Overload and MDS

    ... Anemia , having low number of red blood cells (RBC), affects 80% of patients with MDS, with a substantial ... a short period of time. The amount of iron in a single RBC transfusion is the same as 1,280 cups of cooked spinach. The buildup of iron in ...

    Research Review last updated 05/02/2016 - 9:18am.

  5. HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy (RAFA)

    ... regimen plus a CD34+ selected T-cell depleted peripheral blood stem cell (PBSC) stem cell transplant for the treatment of ... with Fanconi anemia presenting with severe marrow failure (transfusion dependent) or myelodysplastic syndrome, or acute myelogenous ...

    Clinical Trial last updated 04/28/2016 - 8:44am.

  6. MDS Drug Therapy

    ... sub-types of MDS Lenalidomide (Revlimid®) for transfusion-dependent MDS patients with isolated del(5q) and with a low or ... had some positive response to treatment, meaning that blood counts went up. The percentage of patients still surviving after two ...

    Topic section last updated 03/10/2016 - 11:26pm.

  7. Biparental HLA Haplotype Disparate T-cell Depleted Transplants for Patients Lacking an HLACompatible Donor

    ... of a specific kind of transplant. In this transplant, blood from two donors will be used. Each donor will share one half of your HLA ... (MDS): RA/RCMD with high risk cytogenetic features or transfusion dependence, RAEB-1 and RAEB-2 and Acute myelogenous leukemia ...

    Clinical Trial last updated 04/29/2016 - 1:59pm.

  8. Allogeneic Bone Marrow Transplantation Using Less Intensive Therapy

    ... stem cell transplant may be able to replace blood-forming cells that were destroyed by chemotherapy and radiation ... (RA) or all IPSS categories if severe pancytopenia , transfusion requirements not responsive to therapy, or high risk ...

    Clinical Trial last updated 05/02/2016 - 2:20pm.

  9. A Pilot, Phase I/II Study of the Amino Acid Leucine in the Treatment of Patients With Transfusion-Dependent Diamond Blackfan Anemia (LeucineDBA)

    ... form of a capsule and will be taken three times daily. Blood hemoglobin levels will be monitored every 3-4 weeks for 9 months. ... Subjects must be two years of age or older and on transfusion for more than six months prior to enrollment. ...

    Clinical Trial last updated 04/28/2016 - 8:40am.

  10. Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation

    ... after transplant. Eligibility: - Adults 18 70 with blood or bone marrow cancer with no HLA-matched sibling, but with a ... risk: Hemoglobin < 10 g/dl, or > 10 g/dl with transfusion dependence. WBC < 4,000 or > 30,000/mm3 or requires ...

    Clinical Trial last updated 04/29/2016 - 1:00pm.