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  1. Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow

    ... The are a variety of cancerous diseases of the blood and bone marrow that can be potentially cured by bone marrow ... with either life-threatening thrombosis , cytopenia, transfusion dependence or recurrent and debilitating hemolytic crisis. ...

    Clinical Trial last updated 04/28/2016 - 2:08pm.

  2. Preventing Stem Cell Transplant Complications With a Blood Separator Machine

    ... (GVHD) . This complication happens when certain white blood cells from the donor attack the recipient's own body. Researchers want to ... of these categories - refractory anemia with transfusion dependence, refractory anemia with ANC< 500/microL, refractory ...

    Clinical Trial last updated 05/23/2016 - 10:57am.

  3. Donor Stem Cell Transplant in Treating Patients With High Risk Acute Myeloid Leukemia

    ... doses of chemotherapy before a donor peripheral blood stem cell transplant helps stop the growth of cancer cells. It may ... involvement of disease Hemoglobin > 8.0 gm/dL, transfusion allowed Serum creatinine < 2.0 x the upper limits of ...

    Clinical Trial last updated 06/13/2016 - 3:31pm.

  4. Randomized HaploCord Blood Transplantation vs. Double Umbilical Cord Blood Transplantation for Hematologic Malignancies

    ... low frequency of delayed opportunistic infections, reduced transfusion requirements, shortened length of hospital stay and promising long term outcomes. We also hypothesize that umbilical cord blood selection can prioritize matching and better matched donors can be ...

    Clinical Trial last updated 04/29/2016 - 1:15pm.

  5. Personalized Natural Killer (NK) Cell Therapy in Cord Blood Transplantation (CBT)

    ... what is described above. CD20 is a type of marker for white blood cells. White blood cells help protect the body from infections. NK ... revised IPSS intermediate and high risk groups, 2) MDA with transfusion dependency, 3) failure to respond or progression of disease on ...

    Clinical Trial last updated 06/06/2016 - 10:28am.

  6. Safety and Effect of GL-ONC1 Administered IV With or Without Eculizumab Prior to Surgery to Patients With Solid Organ Cancers Undergoing Surgery

    ... × 109; Platelets ≥ 100 × 109 (without platelet transfusion ); Hemoglobin ≥ 9.0 g/dL(with or without red blood cell (RBC) transfusion); Serum creatinine ≤ 1.5 × upper limit ...

    Clinical Trial last updated 04/28/2016 - 1:57pm.

  7. Reduced Intensity Conditioning in Patients Aged ≤35 With Non-Malignant Disorders Undergoing UCBT, BMT, or PBSCT (RIC HSCT NMD)

    ... (MUD) bone marrow transplant (BMT) or peripheral blood stem cell transplant (PBSCT) in patients with non-malignant disorders ... Blackfan Anemia (DBA) • other congenital transfusion dependent anemias Patients with sickle disease must have one or ...

    Clinical Trial last updated 06/13/2016 - 2:18pm.

  8. Eltrombopag With Standard Immunosuppression for Severe Aplastic Anemia

    ... are partial, with only a few patients achieving normal blood counts. Furthermore, analysis of our own extensive clinical data suggests ... to a single course of ATG (non-robust responders), even when transfusion-independence is achieved, predicts a worse prognosis than when ...

    Clinical Trial last updated 04/25/2016 - 2:47pm.

  9. MDS Patient Becomes a Role Model

    ... and things became very serious. Because the MDS affected our blood counts, and in turn our immune systems, we both caught rare infections ... centers, and nursing homes. She has to get a blood transfusion about once a week now. Because everything happened so suddenly, ...

    Patient Chronicle last updated 04/22/2016 - 5:19pm.

  10. Inducible Regulatory T Cells (iTregs) in Non-Myeloablative Sibling Donor Peripheral Blood Stem Cell Transplantation

    ... HLA -identical sibling donor peripheral blood stem cell (PBSC) transplantation for the treatment of a high risk ... syndrome with severe pancytopenia , leading to either transfusion dependency or increased risk for infections Performance ...

    Clinical Trial last updated 04/29/2016 - 1:48pm.