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  1. Early treatment initiation in lower-risk myelodysplastic syndromes produces an earlier and higher rate of transfusion independence

    ... resulting in refractory cytopenias. Red blood cell (RBC) transfusions can improve anemia ; however, prolonged transfusion dependence (TD) is associated with increased morbidity and ...

    Research Article last updated 09/13/2017 - 8:58am.

  2. Luspatercept for the treatment of anaemia in patients with lower-risk myelodysplastic syndromes (PACE-MDS): a multicentre, open-label phase 2 dose-finding study with long-term extension study

    ... chronic myelomonocytic leukaemia ( white blood cell count <13 000/μL), and had anaemia with or without red blood cell transfusion support. Enrolled patients were classified as having low ...

    Research Article last updated 09/18/2017 - 1:38pm.

  3. Progress in Myelodysplastic Syndromes: Clinicopathologic Correlations and Immune Checkpoints

    ... The findings correlated with the recovery of peripheral blood counts and transfusion independency. CONCLUSION: BM morphology and PD-L1 ...

    Research Article last updated 09/11/2017 - 8:59am.

  4. Jill Minden’s Encounter with Aplastic Anemia

    ... doctor told me to go to the hospital right away because my blood counts were extremely low. I had no idea what that meant at the time, and ... I responded better, and my counts were able to stay above transfusion level for a little over a year. T.J. and I got married in 2009 and ...

    Patient Chronicle last updated 09/05/2017 - 10:57am.

  5. Outcomes and healthcare utilization in children and young adults with aplastic anemia: A multiinstitutional analysis

    ... Journal Title:  Pediatr Blood Cancer Primary Author:  ... interval [CI] 0.6-2.58, P = 0.567), while every platelet transfusion was associated with higher mortality (OR 1.37, 95% CI ...

    Research Article last updated 07/18/2017 - 10:32am.

  6. Gouldsmith Family Pulls Together for Gabby

    ... risking of further infection. Tests and the usual blood work were completed and results came back showing severe pancytopenia ... go there immediately. We left on a Friday and she had a transfusion the next day. At this point, they thought it could be leukemia. The ...

    Patient Chronicle last updated 07/06/2017 - 9:40am.

  7. Solving Emma’s Diagnostic Mystery

    ... elevated and sent us to a second hospital. After extensive blood panels and scans, they still couldn’t determine the cause of Emma’s ... showed her platelets had now reached a critical level, a transfusion became necessary to even complete the recommended tests. That ...

    Patient Chronicle last updated 06/15/2017 - 4:38pm.

  8. Denise Beauchemin - My Life is Making a Difference

    ... it was serious and even thought it could be leukemia. Blood tests were done, and when my doctor saw the results he called and told me ... began to respond. By the end of May, I had my last red cell transfusion and by early June had my last platelet transfusion . One ...

    Patient Chronicle last updated 04/12/2017 - 7:12am.

  9. South African Girl with PRCA Gets German Match

    ... bone marrow has gone on strike and she’s not making red blood cells. What caused it remains a mystery, which has stumped doctors from ... levels dropped dangerously low she was given a blood transfusion . The intervals between transfusions became shorter and ...

    Patient Chronicle last updated 03/06/2017 - 3:22pm.

  10. Red Blood Cell Transfusion Dependency and Hyperferritinemia Are Associated with Impaired Survival in Patients Diagnosed with Myelodysplastic Syndromes: Results from the First Polish MDS-PALG Registry

    ... are the only treatment option for about 40% of patients. Transfusion-dependent patients develop secondary iron overload . The ... of the relationship of SF concentration with red blood cell transfusion dependency, survival and transformation to acute ...

    Research Article last updated 10/06/2016 - 1:01pm.