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  1. Myelodysplastic Syndromes and autoimmune disorders: Cause or consequence?

    ... is most common in refractory anemia with excess blasts (RAEB) and chronic myelomonocytic leukemia (CMML). Sweet’s ...

    Research Review last updated 05/02/2016 - 9:18am.

  2. T-cell Depleted Alternative Donor Transplantation

    ... leukemia must be in morphological remission (< 5% blasts ) at the time of transplant. Patients with acute non-lymphocytic ... when aplastic after chemotherapy or with < 20% blasts. Patients with lymphoma must be in complete or close to complete ...

    Clinical Trial last updated 04/29/2016 - 3:38pm.

  3. What does it mean when my doctor says I have had a partial response to a drug treatment?

    ... no blast cells in the blood and a normal number of blasts cells in the bone marrow. A partial response is less than a ...

    FAQ last updated 03/15/2016 - 11:47pm.

  4. What is AML?

    ... your bone marrow being young white blood cells ( blasts ). About 30 out of 100 people with MDS will develop AML. Certain ...

    FAQ last updated 03/15/2016 - 11:27pm.

  5. Inducible Regulatory T Cells (iTregs) in Non-Myeloablative Sibling Donor Peripheral Blood Stem Cell Transplantation

    ... by hematological recovery (ANC > 0.5x 109/L), AND <5% blasts by light microscopy within the bone marrow with a ... by hematological recovery (ANC > 0.5x 109/L), AND <5% blasts by light microscopy within the bone marrow with a cellularity of ≥15%. ...

    Clinical Trial last updated 04/29/2016 - 1:48pm.

  6. Donor Lymphocyte Infusion (DLI) of T-cells Genetically Modified With iCasp9 Suicide Gene

    ... are eligible if they have < 10% bone marrow blasts , and no circulating blasts. b. Myelodysplastic syndrome with intermediate or high risk IPSS score, ...

    Clinical Trial last updated 06/06/2016 - 12:41pm.

  7. Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts for the Prevention of GVHD in Children

    ... 10,000/mm^3 Refractory anemia with excess blasts (RAEB-1 and RAEB-2) Chronic myelogenous leukemia with a history ...

    Clinical Trial last updated 06/13/2016 - 2:29pm.

  8. Total Marrow Irradiation for Refractory Acute Leukemia

    ... syndrome ≤ 55 years of age and ≥ 10% blasts , not responsive to hypomethylating agents and/or conventional ... (pediatric patients <18 years) Not in remission (10-30% blasts in the bone marrow for adult patients ≥18 years and ≤ 55 ...

    Clinical Trial last updated 05/02/2016 - 9:22am.

  9. Donor Stem Cell Transplant in Treating Patients With High Risk Acute Myeloid Leukemia

    ... Organization (WHO) diagnostic criteria (at least 20% blasts in the peripheral blood or bone marrow ), with ...

    Clinical Trial last updated 06/13/2016 - 3:31pm.

  10. Selective Depletion of CD45RA+ Naive T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors for Prevention of GVHD

    ... A or C only) Refractory anemia with excess blasts (RAEB-1 and RAEB-2) (if the patient has received previous induction ...

    Clinical Trial last updated 06/06/2016 - 2:55pm.