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  1. Intra-Osseous Co-Transplant of UCB and hMSC

    ... (CR2) or third complete remission (CR3) ≤ 10% blasts in the marrow and/or ≤ 5% blasts in the peripheral blood Acute lymphoblastic leukemia ...

    Clinical Trial last updated 05/02/2016 - 11:15am.

  2. MDS - Treatment (OLD)

    ... abnormal bone marrow cells  Reduce the number of blasts (young white blood cells) in your bone marrow that have an abnormal ... between 0 and 1.0 Do not usually have an excess of blasts in the bone marrow This type of care includes: ...

    Topic section last updated 03/10/2016 - 11:01pm.

  3. Personalized Natural Killer (NK) Cell Therapy in Cord Blood Transplantation (CBT)

    ... 4) refractory anemia with excess of blasts , 5) transformation to acute leukemia, 6) chronic myelomonocytic ...

    Clinical Trial last updated 06/06/2016 - 10:28am.

  4. Oral Azacitidine (CC-486) for the Treatment of Myelodysplastic Syndromes and Acute Myeloid Leukemia

    ... in many countries for the treatment of AML with 20%-30% blasts and multilineage dysplasia according to the World Health ... of azacitidine treatment of patients with AML with >30% blasts have also been shown in a recent phase III trial. Oral administration of ...

    Research Article last updated 12/09/2015 - 8:49am.

  5. Reduced Intensity Conditioning and Haploidentical Related Bone Marrow for Patients With Hematologic Diseases

    ... morphologic relapse/ persistent disease defined as > 5% blasts in normocellular bone marrow OR any % blasts if blasts have unique morphologic markers (e.g. Auer rods) or associated ...

    Clinical Trial last updated 06/06/2016 - 10:54am.

  6. A Study of E6201 for the Treatment of Advanced Hematologic Malignancies With FLT3 Mutation (AML)

    ... MDS/CMML (defined as ≥ 10% peripheral blood or marrow blasts and international Prognostic Scoring System [IPSS] score ≥ ...

    Clinical Trial last updated 05/09/2016 - 4:09pm.

  7. Hematopoietic Stem Cell Transplantation in High Risk Patients With Fanconi Anemia

    ... in patients with refractory anemia with excess blasts , refractory anemia with excess blasts in transformation, or acute myeloid leukemia treated with this regimen ...

    Clinical Trial last updated 04/28/2016 - 8:49am.

  8. Study of Clinical Efficacy and Safety of Tosedostat in MDS (IST-CTI-MDS)

    ... adult patients with pathologically confirmed MDS (< 20% blasts in bone marrow , peripheral blood, or both) by World Health ...

    Clinical Trial last updated 05/03/2016 - 9:46am.

  9. Allo HSCT Using RIC for Hematological Diseases

    ... be in CR as defined by hematological recovery, AND <5% blasts by light microscopy within the bone marrow with a ... <21 years, however, are eligible with (M2 marrow) with < 25% blasts in marrow after having failed one or more cycles of chemotherapy ...

    Clinical Trial last updated 05/02/2016 - 9:29am.

  10. Dose Escalation of OXi4503 as Single Agent and Combination With Cytarabine w/Subsequent Ph 2 Cohorts for AML and MDS (AML)

    ... or morphologic complete remission or MDS - Marrow blasts must be > 5% and disease failed at least 1 prior hypomethylating ...

    Clinical Trial last updated 05/02/2016 - 11:06am.