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  1. Mesenchymal stromal cell density is increased in higher grade myelodysplastic syndromes and independently predicts survival

    ... 125 cytopenic patients: 40 lower grade MDS (<5% marrow blasts ), 24 higher grade MDS, and 61 benign. RESULTS: CD271+ MSC ...

    Research Article last updated 11/25/2014 - 8:57am.

  2. Clinical and genetic predictors of prognosis in myelodysplastic syndromes

    ... blood cytopenias, the proportion of bone marrow blasts , and specific karyotype abnormalities. Other factors including age, ...

    Research Article last updated 06/19/2014 - 1:30pm.

  3. A Meta-Analysis of the Relationship between Cigarette Smoking and Incidence of Myelodysplastic Syndromes.

    ... with ringed sideroblasts (RARS) or RA with excess blasts (RAEB)/RAEB in transformation (RAEBt), respectively. Our results ...

    Research Article last updated 04/29/2016 - 12:57pm.

  4. Myelodysplastic syndromes

    ... marrow with dysplasia, with or without excess of blasts . Prognosis depends largely on the marrow blast percentage, number ...

    Research Article last updated 04/16/2014 - 12:04pm.

  5. Platelet count doubling after the first cycle of azacitidine therapy predicts eventual response and survival in patients with myelodysplastic syndromes and oligoblastic acute myeloid leukaemia but does not add to prognostic utility of the revised IPSS

    ... acute myeloid leukaemia (<30% bone marrow blasts , n = 102), there was a statistically significant reduction in ...

    Research Article last updated 08/04/2014 - 8:37am.

  6. Lenalidomide as a disease-modifying agent in patients with del(5q) myelodysplastic syndromes: linking mechanism of action to clinical outcomes.

    ... such as additional chromosomal abnormalities, >5 % blasts in the bone marrow (BM), or transfusion dependence. Over ...

    Research Article last updated 09/17/2013 - 2:05pm.

  7. Phase 2 study of the lenalidomide and azacitidine combination in patients with higher-risk myelodysplastic syndromes.

    ... included Intermediate-1 (n=5 patients with excess blasts ), Intermediate-2 (20), and High (11). Common grade 3/4 ...

    Research Article last updated 10/01/2012 - 9:58am.

  8. 5-Azacitidine efficacy and safety in patients aged >65 years with myelodysplastic syndromes outside clinical trials

    ... patients with refractory anemia with excess of blasts (RAEB) type 1, 18 patients with RAEB type 2 and four patients with ...

    Research Article last updated 06/15/2012 - 2:13pm.

  9. Paroxysmal nocturnal hemoglobinuria in pediatric patients.

    ... myelodysplastic features without developing excessive blasts or leukemic transformation. Thrombosis occurred in 6 patients. Five ...

    Research Article last updated 12/12/2011 - 10:07am.

  10. Prognosis of myelodysplastic syndromes.

    ... that include morphological features, percentage of blasts , and clinical and molecular characteristics such as peripheral ...

    Research Article last updated 10/11/2011 - 5:58pm.