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  1. Allogeneic Stem Cell Transplant With Alpha/Beta T AND B Cell Depletion for Hematologic Malignancies (AB-CliniMACs)

    ... is a single arm pilot study for patients using α/β T cell -depleted PSCT in with alternative donor sources with hematologic ... leukemia Disease status: chronic phase, accelerated phase or blast crisis now in second chronic phase. Mixed lineage or biphenotypic ...

    Clinical Trial last updated 06/06/2016 - 3:10pm.

  2. Allogeneic Stem Cell Transplant With Alpha/Beta T AND B Cell Depletion for Hematologic Malignancies (AB-CliniMACs)

    ... is a single arm pilot study for patients using α/β T cell -depleted PSCT in with alternative donor sources with hematologic ... leukemia Disease status: chronic phase, accelerated phase or blast crisis now in second chronic phase. Mixed lineage or biphenotypic ...

    Clinical Trial last updated 06/03/2016 - 2:45pm.

  3. Growth Factors

    ... Red Cell Growth Factor Red cell growth ... white cell growth factors can increase the growth of blast cells in patients with high-risk MDS. This can be a serious problem. For ...

    Topic section last updated 04/06/2016 - 12:37pm.

  4. Allogeneic Bone Marrow Transplantation Using Less Intensive Therapy

    ... RATIONALE: A peripheral stem cell transplant may be able to replace blood-forming cells that were ... leukemia Chronic myelogenous leukemia all types except blast crisis (note treated blast crisis in chronic phase is eligible). ...

    Clinical Trial last updated 05/02/2016 - 2:20pm.

  5. Palifermin With Leuprolide Acetate for the Promotion of Immune Recovery Following Total Body Irradiation Based T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation

    ... help the immune system recover faster following a stem cell transplant . Blood stem cells are very young blood cells that ... second chronic phase, or in CR after accelerated phase or blast crisis. Non-Hodgkins lymphoma with chemo responsive disease in any of ...

    Clinical Trial last updated 04/29/2016 - 1:11pm.

  6. Preventing Stem Cell Transplant Complications With a Blood Separator Machine

    ... Background: - Researchers are working to make stem cell transplant procedures safer and more effective. One complication of ... inhibitors OR Subjects ages 10-80 in accelerated phase or blast transformation. OR 5.1.2.2 Acute lymphoblastic leukemia (ALL): any of ...

    Clinical Trial last updated 05/23/2016 - 10:57am.

  7. A Phase III, International, Randomized, Controlled Study of Rigosertib versus Physician’s Choice of Treatment in Patients with Myelodysplastic Syndrome after Failure of a Hypomethylating Agent

    ... eligible for, or opted not to participate in allogenic stem cell transplantation h. Off all other treatments for MDS (including AZA ... diagnosed with AML (defined as a bone marrow blast percentage of >30%) d.         Suitable candidate to receive ...

    Clinical Trial last updated 11/29/2016 - 8:29am.

  8. Inducible Regulatory T Cells (iTregs) in Non-Myeloablative Sibling Donor Peripheral Blood Stem Cell Transplantation

    ... HLA -identical sibling donor peripheral blood stem cell (PBSC) transplantation for the treatment of a high risk malignancy. Up to ... of ≥15%. Chronic myelogenous leukemia all types except blast crisis (note treated blast crisis in chronic phase is eligible) ...

    Clinical Trial last updated 04/29/2016 - 1:48pm.

  9. San Diego Family Takes Action for Awareness

    ... remained in high-risk status he wasn’t qualified, as his blast count had actually increased. We thought things over for a month or two, ... he no longer needed transfusions. A search for a stem cell donor had been started prior to this treatment. Because David is ...

    Patient Chronicle last updated 10/26/2016 - 11:42am.

  10. MDS - Treatment (OLD)

    ... change over time. As blood counts go lower and bone marrow blast counts rise, your doctor will discuss other treatment options. ... May or may not need blood transfusions, depending on blood cell counts Have a low or intermediate-1 risk IPSS score, which is between ...

    Topic section last updated 03/10/2016 - 11:01pm.