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  1. Prior allogeneic transplant Karnofsky Performance Score < 70% Active central nervous system (CNS) involvement by malignant cells Patients with uncontrolled bacterial, viral or fungal infections (currently taking medication and with progre

    ... =< 1.7 mg/dL (males age >= 16 years) Total bilirubin =< 1.5 x upper limit of normal (ULN) for age Serum glutamic ...

    Clinical Trial last updated 06/06/2016 - 2:05pm.

  2. Phase I/II MAHCT w/ TCell Depleted Graft w/ Simultaneous Infusion Conventional and Regulatory T Cell

    ... < 2.5 x ULN, unless elevated secondary to disease. Total bilirubin < 2 x ULN (patients with Gilbert's syndrome may be included at ...

    Clinical Trial last updated 05/09/2016 - 3:58pm.

  3. SL-401 in Advanced, High Risk Myeloproliferative Neoplasms (Systemic Mastocytosis, Advanced Symptomatic Hypereosinoophic Disorder, Myelofibrosis, Chronic Myelomonocytic Leukemia)

    ... Serum albumin ≥3.0 g/dL (or ≥30 g/L) Bilirubin ≤1.5 mg/dL (or ≤26 µmol/L) Aspartate transaminase (AST) ...

    Clinical Trial last updated 06/06/2016 - 2:11pm.

  4. Pegylated Interferon Alfa-2a Salvage Therapy in High Risk Polycythemia Vera (PV) or Essential Thrombocythemia (ET)

    ... AST and ALT < 2 x upper limit of normal Total bilirubin within normal limits ... AST and ALT > 2 x upper limit of normal Total bilirubin > 1.5 mg/ml No detectable PNH ( paroxysmal nocturnal ...

    Clinical Trial last updated 04/29/2016 - 9:59am.

  5. Phase I, Dose Escalation Study of Decitabine

    ... (ALT) greater than 3 times normal or serum total bilirubin greater than 2 mg/dL; ...

    Clinical Trial last updated 06/06/2016 - 9:44am.

  6. Randomized HaploCord Blood Transplantation vs. Double Umbilical Cord Blood Transplantation for Hematologic Malignancies

    ... organ and marrow function as defined below: Serum bilirubin < 2.0mg/dL ALT(SGPT) 3 X upper limit of normal Creatinine ...

    Clinical Trial last updated 04/29/2016 - 1:15pm.

  7. Microtransplantation to Treat Refractory or Relapsed Hematologic Malignancies in Younger Patients

    ... organ function defined as the following: Total bilirubin ≤ upper limit of normal (ULN) for age, or if total bilirubin is > ULN, direct bilirubin is ≤ 1.5 mg/dL AST (SGOT)/ALT (SGPT) ...

    Clinical Trial last updated 05/09/2016 - 3:01pm.

  8. Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203)

    ... in one second (FEV1) ≥ 50% Liver function: total bilirubin < 1.5 x the upper limit of normal and alanine aminotransferase ... with Gilbert's Disease are allowed to exceed the defined bilirubin value of 1.5x the upper limit of normal. Female subjects (unless ...

    Clinical Trial last updated 06/06/2016 - 1:59pm.

  9. Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

    ... for the research participant's age group Serum bilirubin =< 3.0 mg/dL Alanine aminotransferase (ALT) and aspartate ... Liver Function: adequate liver function defined as total bilirubin =< 3.0 mg/dl Neurological: research participant without ...

    Clinical Trial last updated 07/14/2016 - 4:08pm.

  10. Safety and Efficacy of Two Doses of ATIR101, a T-lymphocyte Enriched Leukocyte Preparation Depleted of Host Alloreactive T-cells, in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donor

    ... or MUGA) AST > 2.5 x ULN (CTCAE grade 2) Bilirubin > 1.5 x ULN (CTCAE grade 2) Creatinine clearance < 50 mL/min ...

    Clinical Trial last updated 04/29/2016 - 12:25pm.