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  1. San Diego Family Takes Action for Awareness

    ... the hematologist explained the three FDA approved drugs, azacitidine , decitabine , and lenalidomide – noting of ... of MDS, which David did not have – and he was put on azacitidine. We also learned a clinical study of oral azacitidine – taken by ...

    Patient Chronicle last updated 10/26/2016 - 11:42am.

  2. AC220 With 5-Aza or Low Dose Cytarabine

    ... of AC220 (quizartinib) that can be given with either 5- azacitidine (azacitidine) or cytarabine to patients with AML or MDS. The goal of the ...

    Clinical Trial last updated 05/03/2016 - 11:11am.

  3. A Safety and Pharmacology Study of Atezolizumab (MPDL3280A, Anti-PD-L1 Antibody) Administered Alone or in Combination With Azacitidine in Patients With Myelodysplastic Syndromes

    ... populations, including treatment in combination with azacitidine . Status:  ... Associated Drug(s):  Azacitidine Phase:  ...

    Clinical Trial last updated 04/27/2016 - 9:57am.

  4. Vidaza and Valproic Acid Post Allogeneic Transplant for High Risk AML and MDS

    ... Phase II trial combining azacitidine with valproic acid as maintenance therapy post allogeneic stem ... MDS/AML. We hypothesize that adding valproic acid to azacitidine will improve outcomes via both direct anti-tumor and ... is near 40%. We hypothesize that valproic acid and azacitidine will prolong survival, with a 1 year survival goal of 60%. In ...

    Clinical Trial last updated 04/29/2016 - 12:35pm.

  5. Lirilumab and Nivolumab With 5-Azacitidine in Patients With Myelodysplastic Syndromes (MDS)

    ... Opdivo (nivolumab), alone or in combination with Vidaza ( azacitidine ), can help to control MDS. The safety of these drug ... Associated Drug(s):  Azacitidine Phase:  ...

    Clinical Trial last updated 04/29/2016 - 11:16am.

  6. Nivolumab and Ipilimumab With 5-azacitidine in Patients With Myelodysplastic Syndromes (MDS)

    ... to learn if nivolumab and/or ipilimumab, with or without azacitidine , are safe to give to patients with MDS. Researchers also want ... Associated Drug(s):  Azacitidine Phase:  ...

    Clinical Trial last updated 04/28/2016 - 2:01pm.

  7. Phase 1 Study to Evaluate MEDI4736 in MDS

    ... of MEDI4736 monotherapy and MEDI4736 in combination with azacitidine in adult patients with myelodysplastic syndrome. ... Associated Drug(s):  Azacitidine Phase:  ...

    Clinical Trial last updated 04/27/2016 - 12:43pm.

  8. New therapeutics for myelodysplastic syndromes

    ... lenalidomide (Revlimidâ) and the azanucleosides, azacitidine (Vidazaâ) and decitabine (Dacogenâ).  Although these ... Targeting the MDS clone:   The azanucleosides (azacitidine and decitabine) remain the best treatment option for many ...

    Research Review last updated 05/02/2016 - 9:28am.

  9. Sorafenib Plus 5-Azacitidine Initial Therapy of Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MS) With FLT3-ITD Mutation

    ... of this clinical research study is to learn if 5- azacitidine and sorafenib can help to control the disease in patients with ... Associated Drug(s):  Azacitidine Phase:  ...

    Clinical Trial last updated 04/29/2016 - 12:23pm.

  10. More is better: Combination therapies for myelodysplastic syndromes

    ... FDA-approved medications for MDS: lenalidomide , azacitidine , and decitabine .  Although these agents can be ... therapy is using an epigenetic approach, where one combines azacitidine or decitabine (the class of drugs known as hypomethylating agents) ...

    Research Review last updated 05/02/2016 - 9:14am.