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  1. Sirolimus and Azacitidine in Treating Patients With High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia That is Recurrent or Not Eligible for Intensive Chemotherapy

    ... This phase II trial studies how well sirolimus and azacitidine works in treating patients with ... for cell growth. Drugs used in chemotherapy , such as azacitidine, work in different ways to stop the growth of cancer cells, either ... the cells or by stopping them from dividing. Sirolimus and azacitidine may kill more cancer cells. Status:  ...

    Clinical Trial last updated 04/28/2016 - 1:13pm.

  2. A Study of Eltrombopag or Placebo in Combination With Azacitidine in Subjects With International Prognostic Scoring System (IPSS) Intermediate-1, Intermediate-2 or High-risk Myelodysplastic Syndromes (MDS)

    ... Approximately 55 subjects will be enrolled into the azacitidine . Subjects with intermediate-1, intermediate-2 or high risk MDS ... combination with the standard of care hypomethylating agent, azacitidine. The primary objective of this study is to determine the effect of ...

    Clinical Trial last updated 04/27/2016 - 1:28pm.

  3. Dose-Escalation Study of FT-2102 as a Single Agent and in Combination With Azacitidine in Patients With AML or MDS With an IDH1 Mutation

    ... PK, and PD of FT-2102 (single agent) and FT-2102 + azacitidine (combination agent) administered via one or more intermittent ... Associated Drug(s):  Azacitidine Phase:  Phase 1 ...

    Clinical Trial last updated 04/29/2016 - 1:06pm.

  4. Study of Vadastuximab Talirine (SGN-CD33A; 33A) in Combination With Azacitidine in Patients With Previously Untreated Higher Risk MDS

    ... of vadastuximab talirine (SGN-CD33A; 33A) and azacitidine in subjects with previously untreated International ... Associated Drug(s):  Azacitidine Phase:  Phase 1 ...

    Clinical Trial last updated 04/29/2016 - 12:55pm.

  5. Vosaroxin and Azacitidine in Treating Patients With Myelodysplastic Syndromes

    ... and the best dose of vosaroxin when given together with azacitidine in treating patients with myelodysplastic syndromes. Drugs used in chemotherapy , such as vosaroxin and azacitidine, work in different ways to stop the growth of cancer cells, either ...

    Clinical Trial last updated 04/28/2016 - 3:36pm.

  6. Ibrutinib and Azacitidine for Treatment of Higher Risk Myelodysplastic Syndrome

    ... and best dose of ibrutinib when given together with azacitidine in treating patients with myelodysplastic syndrome that is ... and unfit for or refused intense therapy. Ibrutinib and azacitidine may stop the growth of cancer cells by blocking some of the enzymes ...

    Clinical Trial last updated 04/27/2016 - 9:44am.

  7. Randomized Allogeneic Azacitidine Study

    ... clinical research study is to learn if Vidaza ( azacitidine ) will help to control the disease in patients with AML, CMML, ... Associated Drug(s):  Azacitidine Phase:  Phase 3 ...

    Clinical Trial last updated 05/03/2016 - 11:08am.

  8. Trial of Volasertib With or Without Azacitidine in Patients With Myelodysplastic Syndromes

    ... volasertib as monotherapy or in combination with azacitidine in patients with myelodysplastic syndrome (MDS) after ... Associated Drug(s):  Azacitidine Phase:  Phase 1 ...

    Clinical Trial last updated 04/28/2016 - 3:43pm.

  9. A Combination Study of PF-04449913 and Azacitidine In 1st Line MDS, AML and CMML Patients

    ... (PD) of PF 04449913 or placebo when combined with azacitidine in patients with previously untreated Intermediate 2 or High ... Associated Drug(s):  Azacitidine Phase:  Phase 2 ...

    Clinical Trial last updated 04/27/2016 - 1:20pm.

  10. The Efficacy and Safety of Oral Azacitidine Plus Best Supportive Care Versus Placebo and Best Supportive Care in Subjects With Red Blood Cell (RBC) Transfusion-Dependent Anemia and Thrombocytopenia Due to International Prognostic Scoring System (IPSS) Low

    ... Evaluation of the Efficacy and Safety of Oral Azacitidine plus Best Supportive care versus Placebo and ... Associated Drug(s):  Azacitidine Phase:  Phase 3 ...

    Clinical Trial last updated 04/27/2016 - 9:52am.