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  1. Immunomodulatory Drugs: New Options for the Treatment of Myelodysplastic Syndromes

    ... and antiangiogenic activities, and they also induce the apoptosis of neoplastic cells. Thalidomide and its derivative ...

    Research Article last updated 01/03/2013 - 9:57am.

  2. Pacritinib in Combination With Low Dose Decitabine in Intermediate-High Risk Myelofibrosis or Myeloproliferative Neoplasm (MPN)/Myelodysplastic Syndrome (MDS)

    ... administration may avoid high peak levels that can cause apoptosis . Furthermore, the low toxicity associated with low dose ...

    Clinical Trial last updated 04/29/2016 - 1:59pm.

  3. Myelodysplastic Syndromes and autoimmune disorders: Cause or consequence?

    ... responses can induce bone marrow failure due to apoptosis . Due to increased production of these cytokines and impaired ...

    Research Review last updated 05/02/2016 - 9:18am.

  4. Pediatric MDS

    ... in disturbances  in blood cell differentiation and apoptosis (cell death). It is distinguished from acute myeloid leukemias ...

    Interview last updated 10/24/2012 - 1:31pm.

  5. Neal Young, M.D., MACP

    ... hepatitis viruses, immune response to virus infection, apoptosis , interferon, cytokines, and other interleukins, and the ...

    Leadership Award last updated 07/19/2012 - 11:34am.

  6. Pathogenesis of MDS: An overview of molecular and non-molecular aspects of the disease

    ... MDS is transcription of genes and cell cycle progression/ apoptosis , and genes involved in this pathway include RUNX1, TP53, and ... factors associated with the bone marrow microenvironment, apoptosis, cytokines, telomere length, and immune factors.  ...

    Research Review last updated 05/02/2016 - 9:14am.

  7. Nurse's Corner Summer 2015: Understanding the Etiology and Epidemiology of Myelodysplastic Syndromes

    ... that early in the disease leads to accelerated apoptosis and later to impaired differentiation and proliferation. ...

    Page last updated 07/27/2015 - 12:04pm.