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  1. Immunological derangement in hypocellular myelodysplastic syndromes

    ... to immunosuppression including mainly cyclosporine , anti-thymocyte globulin and/or cyclosporine, or alemtuzumab . Here we review all these ...

    Research Article last updated 05/22/2014 - 9:53am.

  2. Aplastic anemia: what have we learned from animal models and from the clinic.

    ... of responsiveness of AA to immunomodulatory agents such as anti-thymocyte globulin (ATG) and the requirement of cyclosporine to maintain ...

    Research Article last updated 11/21/2013 - 11:26am.

  3. New therapeutic approaches for protecting hematopoietic stem cells in aplastic anemia.

    ... with AA include: (1) immunosuppressive therapy (IST) with anti-thymocyte globulin and cyclosporine A which targets self-reactive T cells, or (2) ...

    Research Article last updated 11/14/2013 - 11:18am.

  4. Diagnosis and treatment of pediatric acquired aplastic anemia (AAA): An initial survey of the North American Pediatric Aplastic Anemia Consortium (NAPAAC)

    ... is identified; the use of first-line IST containing horse anti-thymocyte globulin and cyclosporine A (CSA) if an HLA-identical sibling donor is ...

    Research Article last updated 12/17/2013 - 8:30am.

  5. Allogeneic stem cell transplantation using alemtuzumab-containing regimens in severe aplastic anemia.

    ... low incidence of GVHD makes it an attractive alternative to anti-thymocyte globulin (ATG) in transplant conditioning regimen for severe aplastic anaemia ...

    Research Article last updated 06/20/2013 - 10:30am.

  6. Front-line immunosuppressive treatment of acquired aplastic anemia

    ... briefly illustrated. First-line IST should consist of horse anti-thymocyte globulin (ATG) and CsA that has been shown to result in response rates between ...

    Research Article last updated 01/02/2013 - 2:48pm.

  7. A randomized comparison of cyclophosphamide vs. reduced dose cyclophosphamide plus fludarabine for allogeneic hematopoietic cell transplantation in patients with aplastic anemia and hypoplastic myelodysplastic syndrome.

    ... cyclophosphamide (Cy), fludarabine , and anti-thymocyte globulin (ATG) (Cy-Flu-ATG) was used to condition high-risk patients scheduled ...

    Research Article last updated 05/11/2012 - 2:04pm.

  8. Activity of alemtuzumab monotherapy in treatment-naive, relapsed, and refractory severe acquired aplastic anemia

    ... Anti-thymocyte globulin (ATG) plus cyclosporine is effective in restoring ...

    Research Article last updated 11/16/2011 - 1:57pm.

  9. Clinical management of aplastic anemia.

    ... have a matched sibling donor. Immunosuppression with either anti-thymocyte globulin and cyclosporine or high-dose cyclophosphamide is an ...

    Research Article last updated 10/11/2011 - 5:58pm.

  10. Association of telomere length of peripheral blood leukocytes with hematopoietic relapse, malignant transformation, and survival in severe aplastic anemia.

    ... consecutively enrolled in immunosuppression protocols with antithymocyte globulin plus cyclosporine for correlation with clinical outcomes were ...

    Research Article last updated 10/11/2011 - 5:58pm.