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  1. Common polymorphic deletion of glutathione S-transferase theta predisposes to acquired aplastic anemia: Independent cohort and meta-analysis of 609 patients.

    ... Acquired aplastic anemia (AA) is a rare life-threatening bone marrow failure ... between the GSTT1 null polymorphism and aplastic anemia could be defined using a meta-analysis of 609 aplastic anemia patients, ...

    Research Article last updated 07/09/2013 - 2:58pm.

  2. "Moderate" dose cyclophosphamide for severe aplastic anemia has significant toxicity and does not prevent relapse and clonal evolution.

    ... First line therapy of aplastic anemia with high dose cyclophosphamide causes toxicity and ... Bone Marrow Diseases:  aplastic anemia ...

    Research Article last updated 10/07/2014 - 8:33am.

  3. The diagnosis and treatment of aplastic anemia: a review

    ... Aplastic anemia is a rare disorder characterized by suppression of bone marrow ... Bone Marrow Diseases:  aplastic anemia ...

    Research Article last updated 05/26/2015 - 10:30am.

  4. Dysregulated miR34a/diacylglycerol kinase ζ interaction enhances T-cell activation in acquired aplastic anemia

    ... Acquired aplastic anemia is an idiopathic paradigm of human bone marrow failure ... in bone marrow CD3+ T cells from patients with aplastic anemia and healthy controls. Overexpression of miR34a and underexpression of ...

    Research Article last updated 01/24/2017 - 10:08am.

  5. New study on SCT therapy for SAA, MDS patients

    ... Umbilical Cord Blood Transplant Study Begins for Aplastic Anemia and Hypoplastic MDS ... testing their candidate CordIn, to treat severe aplastic anemia (AA) or hypoplastic myelodysplastic syndrome (MDS) has begun, and ...

    Article last updated 08/22/2017 - 9:41am.

  6. Aplastic anemia: what have we learned from animal models and from the clinic.

    ... Aplastic anemia (AA) is currently perceived as an immune-mediated disease in which ... Bone Marrow Diseases:  aplastic anemia ...

    Research Article last updated 11/21/2013 - 11:26am.

  7. Diagnosis and treatment of pediatric acquired aplastic anemia (AAA): An initial survey of the North American Pediatric Aplastic Anemia Consortium (NAPAAC)

    ... Randomized clinical trials in pediatric aplastic anemia (AA) are rare and data to guide standards of care are scarce. ... institutions formed the North American Pediatric Aplastic Anemia Consortium to foster collaborative studies in AA. The initial goal of ...

    Research Article last updated 12/17/2013 - 8:30am.

  8. Optimizing Cord Blood and Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502) (CHAMP)

    ... haploidentical transplantation for Severe Aplastic Anemia (SAA) patients. The primary objective is to assess overall survival ... Bone Marrow Disease(s):  aplastic anemia Associated Drug(s):  ...

    Clinical Trial last updated 12/19/2017 - 7:55am.

  9. New therapeutic approaches for protecting hematopoietic stem cells in aplastic anemia.

    ... Aplastic anemia (AA) is an immune-mediated and life-threatening form of acquired ... Bone Marrow Diseases:  aplastic anemia ...

    Research Article last updated 11/14/2013 - 11:18am.

  10. Management of the refractory aplastic anemia patient: what are the options?

    ... Refractory aplastic anemia (AA) is defined as lack of response to first line immunosuppressive ... Bone Marrow Diseases:  aplastic anemia ...

    Research Article last updated 09/26/2013 - 3:05pm.