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  1. A Phase III, International, Randomized, Controlled Study of Rigosertib versus Physician’s Choice of Treatment in Patients with Myelodysplastic Syndrome after Failure of a Hypomethylating Agent

    ... not eligible for, or opted not to participate in allogenic stem cell transplantation h. Off all other treatments for MDS (including ... of >30%) d.         Suitable candidate to receive allogeneic stem cell transplantation; patient is eligible for study if a ...

    Clinical Trial last updated 11/29/2016 - 8:29am.

  2. Treosulfan and Fludarabine Phosphate With or Without Total Body Irradiation Before Donor Stem Cell Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia

    ... with or without total body irradiation before donor stem cell transplant works in treating patients with myelodysplastic syndrome ... Intervention:  Procedure: Allogeneic Bone Marrow Transplantation Undergo allogeneic bone marrow ...

    Clinical Trial last updated 04/28/2016 - 1:05pm.

  3. Bone Marrow Transplant

    ... There are two basic types of bone marrow /stem cell transplants. A transplant may use cells taken from a donor or from ... patients with bone marrow failure diseases. Allogeneic transplants use cells from a healthy donor. These might come from ...

    Topic section last updated 03/29/2016 - 7:27pm.

  4. Clofarabine and Melphalan Before Donor Stem Cell Transplant in Treating Patients With Myelodysplasia or Acute Leukemia in Remission

    ... how well clofarabine and melphalan before a donor stem cell transplant works in treating patients with a decrease in or ... mustard L-Sarcolysin Procedure: allogeneic hematopoietic stem cell transplantation Undergo allogeneic ...

    Clinical Trial last updated 05/03/2016 - 11:55am.

  5. Donor Lymphocyte Infusion (DLI) of T-cells Genetically Modified With iCasp9 Suicide Gene

    ... chemotherapy will improve the response to a stem cell transplant . The safety of this treatment will also be studied. ... Hodgkin disease, or MM, after they have received an allogeneic stem cell transplant . The chemotherapy participant will be ...

    Clinical Trial last updated 06/06/2016 - 12:41pm.

  6. Allogeneic Bone Marrow Transplantation Using Less Intensive Therapy

    ... RATIONALE: A peripheral stem cell transplant may be able to replace blood-forming cells that were ...

    Clinical Trial last updated 05/02/2016 - 2:20pm.

  7. Pilot Study of Lupron to Improve Immune Function After Allogeneic Bone Marrow Transplantation

    ... of the blood and immune system is to give a patient stem cells from the bone marrow of a donor whose genes are very ... Intervention:  Procedure: Allogeneic HSC Transplantation Allogeneic HSC Transplantation Drug: ...

    Clinical Trial last updated 04/28/2016 - 11:14am.

  8. AML Therapy With Irradiated Allogeneic Cells

    ... must not be a candidate for an allo-hematopoietic stem cell transplant (HSCT) Patient must have a partially (>= 3/6 class I ...

    Clinical Trial last updated 06/13/2016 - 3:14pm.

  9. REVERSE 1 INCB 18424-271

    ... Criteria:   Have undergone first allogeneic hematopoietic stem cell transplantation (allo-HSCT) from any donor source using bone ...

    Clinical Trial last updated 12/14/2016 - 11:24am.

  10. Hematopoietic Stem Cell Transplant for Dyskeratosis Congenita or Severe Aplastic Anemia

    ... Fludarabine -based preparative regimen followed by an allogeneic hematopoietic stem cell transplant using related or unrelated donor in persons ...

    Clinical Trial last updated 04/25/2016 - 10:59am.