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  1. Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation

    ... Purpose:  Background: - In allogeneic stem cell transplantation (SCT), stem cells are taken from a donor and ...

    Clinical Trial last updated 04/29/2016 - 1:00pm.

  2. Fludarabine Phosphate and Total Body Irradiation Followed by a Donor Peripheral Stem Cell Transplant in Treating Patients With Myelodysplastic Syndromes or Myeloproliferative Disorders

    ... fludarabine phosphate followed by a donor peripheral stem cell transplant in treating patients withmyelodysplastic syndromes ... PO Other Names: Cellcept MMF Procedure: Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation Undergo ...

    Clinical Trial last updated 04/27/2016 - 1:27pm.

  3. Palifermin With Leuprolide Acetate for the Promotion of Immune Recovery Following Total Body Irradiation Based T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation

    ... can help the immune system recover faster following a stem cell transplant . Blood stem cells are very young blood cells ... a family member or a volunteer donor. This is called an allogeneic stem cell transplant . The investigators want to see if ...

    Clinical Trial last updated 04/29/2016 - 1:11pm.

  4. Yttrium Y 90 Anti-CD45 Monoclonal Antibody BC8 Followed by Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome

    ... monoclonal antibody BC8 (90Y-BC8) followed by donor stem cell transplant in treating patients with acute myeloid leukemia ... Intervention:  Procedure: Allogeneic Bone Marrow Transplantation Undergo allogeneic bone marrow ...

    Clinical Trial last updated 04/28/2016 - 1:11pm.

  5. Fludarabine Phosphate and Total Body Irradiation Followed by a Donor Peripheral Stem Cell Transplant in Treating Patients With Myelodysplastic Syndromes or Myeloproliferative Disorders

    ... fludarabine phosphate followed by a donor peripheral stem cell transplant in treating patients with myelodysplastic ... Cellcept MMF Procedure: Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation Undergo ...

    Clinical Trial last updated 04/28/2016 - 2:45pm.

  6. Vidaza and Valproic Acid Post Allogeneic Transplant for High Risk AML and MDS

    ... with valproic acid as maintenance therapy post allogeneic stem cell transplantation in patients with high-risk MDS/AML. We hypothesize ...

    Clinical Trial last updated 04/29/2016 - 12:35pm.

  7. Nonmyeloablative Allogeneic Transplant (Mini-allo)

    ... Purpose:  Allogeneic transplant from a matched sibling for the treatment of a variety of ... Exclusion Criteria: Prior allogeneic stem cell or bone marrow transplant Current or past history of ...

    Clinical Trial last updated 04/28/2016 - 2:13pm.

  8. Youmna Kfoury, PhD

    ... platform of mesenchymal stromal layers and hematopoietic stem and progenitor cells (HSPCs) using a CRISPR-Cas9 based strategy to knock ... of MDS, the only curative therapy remains that of allogeneic stem cell transplant (allo-SCT). The allo-SCT is not the ...

    Grant Recipient last updated 12/15/2016 - 12:56pm.

  9. Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant Diseases

    ... gene modified T cells infused after a haplo-identical stem cell transplant to facilitate engraftment and the safety of ... Patient must meet eligibility criteria for allogeneic transplantation Males or females Age < 55 years old and > 4 ...

    Clinical Trial last updated 06/13/2016 - 1:54pm.

  10. A Phase III, International, Randomized, Controlled Study of Rigosertib versus Physician’s Choice of Treatment in Patients with Myelodysplastic Syndrome after Failure of a Hypomethylating Agent

    ... not eligible for, or opted not to participate in allogenic stem cell transplantation h. Off all other treatments for MDS (including ... of >30%) d.         Suitable candidate to receive allogeneic stem cell transplantation; patient is eligible for study if a ...

    Clinical Trial last updated 11/29/2016 - 8:29am.