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  1. Novel approaches for myelodysplastic syndromes: beyond hypomethylating agents.

    ... index may help select appropriate patients for allogeneic stem cell transplant . A variety of promising new agents are under ...

    Research Article last updated 10/11/2011 - 5:58pm.

  2. Hematopoietic stem cell transplantation for paroxysmal nocturnal hemoglobinuria: long-term results of a retrospective study on behalf of the Gruppo Italiano Trapianto Midollo Osseo (GITMO).

    ... is an acquired clonal disorder of the hemopoietic stem cells for which the only curative treatment is allogeneic hematopoietic stem cell transplantation. DESIGN AND METHODS: ...

    Research Article last updated 10/11/2011 - 5:58pm.

  3. Myelodysplastic syndrome hematopoietic stem cell

    ... syndromes (MDSs) are clonal hematopoietic stem cell (HSC) malignancies that are characterized by ineffective hematopoiesis ... can actually alter the natural history of this disease. Allogeneic stem-cell transplantation for high-risk MDS is becoming the only ...

    Research Article last updated 11/05/2012 - 10:21am.

  4. Optimizing stem cell transplantation in myelodysplastic syndromes: unresolved questions.

    ... PURPOSE OF REVIEW: Allogeneic hematopoietic stem cell transplantation (HCT) is the only curative therapy for ...

    Research Article last updated 10/11/2011 - 5:58pm.

  5. 5-Azacytidine in myelodysplastic syndromes: a clinical practice guideline.

    ... blasts ) who cannot proceed immediately to allogeneic stem cell transplant . 5-Aza is not recommended as first line therapy with ...

    Research Article last updated 10/11/2011 - 5:58pm.

  6. Can G-CSF Cause Leukemia in Hematopoietic Stem Cell Donors?

    ... A large majority of allogeneic hematopoietic stem cell donations are achieved using granulocyte -colony stimulating ...

    Research Article last updated 10/11/2011 - 5:58pm.

  7. Simona Pagliuca, MD

    ... in which the bone marrow and the hematopoietic stem cells that reside there are damaged. This causes a deficiency of all ... reason why main treatment approaches of this disease concern allogeneic hematopoietic stem cell transplantation and immunosuppressive ...

    Grant Recipient last updated 06/08/2017 - 10:43am.

  8. Laboratory tests for paroxysmal nocturnal hemoglobinuria (PNH).

    ... Glycan class A (PIG-A) gene in the hematopoietic stem cells (HSC) of patients. The presence of these mutations leads to ... C5 ( Eculizumab ), anticoagulation, and in some cases allogeneic HSC transplant. In this paper we review the different diagnostic ...

    Research Article last updated 10/22/2013 - 3:44pm.

  9. Transplantation strategies for the management of patients with myelodysplastic syndromes.

    ... October 1, 2009 Allogeneic stem cell transplantation (SCT) is the only therapeutic modality at present ...

    Research Article last updated 10/11/2011 - 5:58pm.

  10. Transplantation for myelodysplastic syndromes 2013.

    ... patients with myelodysplastic syndromes (MDS) is allogeneic haematopoietic stem cell transplantation (HCT). However, many MDS patients are older, often ...

    Research Article last updated 10/22/2013 - 12:53pm.