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  1. Hematopoietic stem cell transplantation for paroxysmal nocturnal hemoglobinuria: long-term results of a retrospective study on behalf of the Gruppo Italiano Trapianto Midollo Osseo (GITMO).

    ... is an acquired clonal disorder of the hemopoietic stem cells for which the only curative treatment is allogeneic hematopoietic stem cell transplantation. DESIGN AND METHODS: ...

    Research Article last updated 10/11/2011 - 5:58pm.

  2. Myelodysplastic syndrome evolving from aplastic anemia treated with immunosuppressive therapy: efficacy of hematopoietic stem cell transplantation.

    ... anemia myelodysplastic syndrome). Many will proceed to allogeneic hematopoietic stem cell transplantation. We identified 123 patients with post-aplastic ...

    Research Article last updated 08/21/2014 - 9:32am.

  3. Myelodysplastic syndrome hematopoietic stem cell

    ... syndromes (MDSs) are clonal hematopoietic stem cell (HSC) malignancies that are characterized by ineffective hematopoiesis ... can actually alter the natural history of this disease. Allogeneic stem-cell transplantation for high-risk MDS is becoming the only ...

    Research Article last updated 11/05/2012 - 10:21am.

  4. Optimizing stem cell transplantation in myelodysplastic syndromes: unresolved questions.

    ... PURPOSE OF REVIEW: Allogeneic hematopoietic stem cell transplantation (HCT) is the only curative therapy for ...

    Research Article last updated 10/11/2011 - 5:58pm.

  5. 5-Azacytidine in myelodysplastic syndromes: a clinical practice guideline.

    ... blasts ) who cannot proceed immediately to allogeneic stem cell transplant . 5-Aza is not recommended as first line therapy with ...

    Research Article last updated 10/11/2011 - 5:58pm.

  6. Can G-CSF Cause Leukemia in Hematopoietic Stem Cell Donors?

    ... A large majority of allogeneic hematopoietic stem cell donations are achieved using granulocyte -colony stimulating ...

    Research Article last updated 10/11/2011 - 5:58pm.

  7. Optimizing Cord Blood and Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502) (CHAMP)

    ... (OS) separately in the 2 arms at 1 year post-hematopoietic stem cell transplantation (HSCT). ... (MFI) > 1000 by solid phase immunoassay). Prior allogeneic stem cell transplant . Prior solid organ transplant. ...

    Clinical Trial last updated 12/19/2017 - 7:55am.

  8. Transplantation strategies for the management of patients with myelodysplastic syndromes.

    ... Allogeneic stem cell transplantation (SCT) is the only therapeutic modality at present ...

    Research Article last updated 10/11/2011 - 5:58pm.

  9. Laboratory tests for paroxysmal nocturnal hemoglobinuria (PNH).

    ... Glycan class A (PIG-A) gene in the hematopoietic stem cells (HSC) of patients. The presence of these mutations leads to ... C5 ( Eculizumab ), anticoagulation, and in some cases allogeneic HSC transplant. In this paper we review the different diagnostic ...

    Research Article last updated 10/22/2013 - 3:44pm.

  10. Transplantation for myelodysplastic syndromes 2013.

    ... patients with myelodysplastic syndromes (MDS) is allogeneic haematopoietic stem cell transplantation (HCT). However, many MDS patients are older, often ...

    Research Article last updated 10/22/2013 - 12:53pm.