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  1. Diagnostic tools in the indications for allogeneic stem cell transplantation in myelodysplastic syndromes.

    ... The rates of allogeneic stem cell transplantation (SCT) to treat the myelodysplastic syndromes ...

    Research Article last updated 10/11/2011 - 5:58pm.

  2. Response to pre-transplant hypomethylating agents influences the outcome of allogeneic hematopoietic stem cell transplantation in adults with myelodysplastic syndromes

    ... The present study describes a retrospective analysis on the transplant outcome of 56 consecutive myelodysplastic syndrome (MDS) patients ...

    Research Article last updated 11/19/2012 - 2:41pm.

  3. Multicenter study evaluating the impact of hypomethylating agents as bridging therapy to hematopoietic stem cell transplantation in myelodysplastic syndromes

    ... Allogeneic hematopoietic stem cell transplantation (alloSCT) is currently the only curative treatment ...

    Research Article last updated 04/16/2014 - 12:24pm.

  4. Myelodysplastic syndromes: Contemporary review and how we treat

    ... syndromes (MDS) are a heterogeneous group of clonal stem cell disorders with an inherent tendency for leukemic transformation. ... lenalidomide for MDS with isolated del(5q). To date, allogeneic stem cell transplant (ASCT) remains the only treatment option ...

    Research Article last updated 04/29/2016 - 1:05pm.

  5. Comparison between Matched Related and Alternative Donors of Allogeneic Hematopoietic Stem Cells Transplanted into Adult Patients with Acquired Aplastic Anemia: Multivariate and Propensity Score-Matched Analysis.

    ... adult acquired aplastic anemia (AA) who underwent allogeneic hematopoietic stem cell transplantation (alloHSCT) from matched related donors (MRDs), and ...

    Research Article last updated 10/11/2011 - 5:58pm.

  6. Personalized medicine for MDS

    ... be considered for a more intensive treatment, such as allogeneic stem cell transplant , earlier in the course of disease.  This personalized ...

    Research Review last updated 05/02/2016 - 9:44am.

  7. NCI First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation: report from the Committee on Disease-Specific Methods and Strategies for Monitoring Relapse following Allogenei

    ... has become the major cause of treatment failure after allogeneic stem cell transplantation. Outcome of patients with clinical relapse after ...

    Research Article last updated 10/11/2011 - 5:58pm.

  8. Syngeneic transplantation in aplastic anemia: pretransplant conditioning and peripheral blood are associated with improved engraftment - an observational study on behalf of the Severe Aplastic Anemia and Pediatric Diseases Working Parties of the European

    ... anemia is usually treated with immunosuppression or allogeneic transplant, depending on patient and disease characteristics. ... and anti-thymocyte globulin as well as peripheral blood stem cells performed in later years. Ten year overall survival was 93% with ...

    Research Article last updated 08/05/2013 - 9:44am.

  9. Pilot trial of risk-adapted cyclophosphamide intensity based conditioning and HLA matched sibling and unrelated cord blood stem cell transplantation in newly diagnosed pediatric and adolescent recipients with acquired severe aplastic anemia

    ... Cyclophosphamide -based conditioning regimens and allogeneic hematopoietic stem cell transplantation (AlloHSCT) from matched related donors (MRD) has ...

    Research Article last updated 04/09/2014 - 9:11am.

  10. Novel approaches for myelodysplastic syndromes: beyond hypomethylating agents.

    ... index may help select appropriate patients for allogeneic stem cell transplant . A variety of promising new agents are under ...

    Research Article last updated 10/11/2011 - 5:58pm.