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  1. TCRαβ+/CD19+ Depleted Haploidentical HSCT + Zoledronate

    ... transplantation with a haploidentical donor peripheral blood stem cell graft depleted of TCRαβ+ cells and CD19+ cells in conjunction with ... occurring < 30 months from diagnosis, relapse after previous allogeneic hematopoietic stem cell transplant [allo-HSCT], relapse ...

    Clinical Trial last updated 04/29/2016 - 4:35pm.

  2. Microtransplantation to Treat Refractory or Relapsed Hematologic Malignancies in Younger Patients

    ... Purpose:  Allogeneic transplant can sometimes be an effective treatment for leukemia. In ... infusion of their donor's bone marrow or blood stem cells . The high-dose chemotherapy drugs and radiation are given to ...

    Clinical Trial last updated 05/09/2016 - 3:01pm.

  3. Laboratory-Treated T Cells in Treating Patients With High-Risk Relapsed Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia Previously Treated With Donor Stem Cell Transplant

    ... of improvement (relapsed), previously treated with donor stem cell transplant . Biological therapies, such as cellular adoptive ... Analysis Correlative studies Biological: WT1-Sensitized Allogeneic T-Lymphocytes Given IV ...

    Clinical Trial last updated 04/29/2016 - 10:34am.

  4. Clinical Trials Report for January 2016

    ... Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies ... has a Fludarabine-based preparative regimen followed by an allogeneic hematopoietic stem cell transplant using related or unrelated ...

    Page last updated 01/07/2016 - 10:57am.

  5. Graft-vs-host-disease (GVHD): Signs, Symptoms, and Treatment

    ... An allogeneic stem cell transplant uses blood-forming cells ( stem cells ) donated by ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  6. Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203)

    ... is an important cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT). This study aims to determine if any of three ...

    Clinical Trial last updated 06/06/2016 - 1:59pm.

  7. Efficacy of Oral Azacitidine Plus Best Supportive Care as Maintenance Therapy in Subjects With Acute Myeloid Leukemia in Complete Remission (QUAZAR AML-001)

    ... of such translocations Prior bone marrow or stem cell transplantation Candidate for allogeneic bone marrow or stem cell transplant Have achieved CR/CRi ...

    Clinical Trial last updated 04/29/2016 - 8:39am.

  8. Azacitidine in Haploidentical Donor Hematopoietic Cell Transplantation

    ... Purpose:  Allogeneic hematopoietic cell transplantation (allo-HCT) is a potentially curative therapy for patients ... Stem cell transplant Drug: Azacitidine Other Names: Vidaza Ladakamycin ...

    Clinical Trial last updated 05/03/2016 - 11:15am.

  9. Interviews with the Experts Managing MDS With Supportive Care and Active Treatment

    ... for MDS, one that is potentially curative, is an allogeneic stem cell transplant , but not all patients are suited for or otherwise ...

    Interview last updated 09/22/2014 - 12:25pm.

  10. Transplantation Update

    ... toxicity from the regimens used to prepare patients for stem cell transplants regardless of who the donor is or the source of stem ... add that even patients who are 70 may be doing well with an allogeneic transplant but if they develop problems, like GVHD and they are then ...

    Interview last updated 05/14/2015 - 2:42pm.