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  1. Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203)

    ... is an important cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT). This study aims to determine if any of three ...

    Clinical Trial last updated 06/06/2016 - 1:59pm.

  2. Microtransplantation to Treat Refractory or Relapsed Hematologic Malignancies in Younger Patients

    ... Purpose:  Allogeneic transplant can sometimes be an effective treatment for leukemia. In ... infusion of their donor's bone marrow or blood stem cells . The high-dose chemotherapy drugs and radiation are given to ...

    Clinical Trial last updated 05/09/2016 - 3:01pm.

  3. TCRαβ+/CD19+ Depleted Haploidentical HSCT + Zoledronate

    ... transplantation with a haploidentical donor peripheral blood stem cell graft depleted of TCRαβ+ cells and CD19+ cells in conjunction with ... occurring < 30 months from diagnosis, relapse after previous allogeneic hematopoietic stem cell transplant [allo-HSCT], relapse ...

    Clinical Trial last updated 04/29/2016 - 4:35pm.

  4. Laboratory-Treated T Cells in Treating Patients With High-Risk Relapsed Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia Previously Treated With Donor Stem Cell Transplant

    ... of improvement (relapsed), previously treated with donor stem cell transplant . Biological therapies, such as cellular adoptive ... Analysis Correlative studies Biological: WT1-Sensitized Allogeneic T-Lymphocytes Given IV ...

    Clinical Trial last updated 04/29/2016 - 10:34am.

  5. Efficacy of Oral Azacitidine Plus Best Supportive Care as Maintenance Therapy in Subjects With Acute Myeloid Leukemia in Complete Remission (QUAZAR AML-001)

    ... of such translocations Prior bone marrow or stem cell transplantation Candidate for allogeneic bone marrow or stem cell transplant Have achieved CR/CRi ...

    Clinical Trial last updated 04/29/2016 - 8:39am.

  6. Azacitidine in Haploidentical Donor Hematopoietic Cell Transplantation

    ... Purpose:  Allogeneic hematopoietic cell transplantation (allo-HCT) is a potentially curative therapy for patients ... Stem cell transplant Drug: Azacitidine Other Names: Vidaza Ladakamycin ...

    Clinical Trial last updated 05/03/2016 - 11:15am.

  7. Recurrent and Secondary MDS

    ... approaches, after medical treatments, and even after an allogeneic stem cell transplant . So, I think of recurrent MDS to mean progression or ...

    Interview last updated 10/24/2012 - 1:12pm.

  8. Clinical Trials Report for January 2016

    ... Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies ... has a Fludarabine-based preparative regimen followed by an allogeneic hematopoietic stem cell transplant using related or unrelated ...

    Page last updated 01/07/2016 - 10:57am.

  9. Clinical Trials Report for April 2014

    ... treated with drugs that suppress the immune system or with stem cell transplant. People with SAA who receive these treatments are more ... determine the incidence of grade II-IV acute GVHD following Allogeneic (allo) Hematopoeitic Cell Transplant (HCT) using post-transplant ...

    Page last updated 04/18/2014 - 3:36pm.

  10. PRO#1278: Fludarabine and Busulfan vs. Fludarabine, Busulfan and Total Body Irradiation (FLUBUTBI)

    ... and low dose total body irradiation in patients undergoing allogeneic stem cell transplantation. A study population of 80 subjects will be enrolled ...

    Clinical Trial last updated 04/29/2016 - 3:09pm.