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  1. Cord Blood Transplant

    ... Purpose:  Allogeneic hematopoietic cell transplantation (allo- HCT) is a curative therapy ... donor is the most commonly used source of allogeneic stem cells . However, HLA matched siblings are available for less than one ...

    Clinical Trial last updated 04/27/2016 - 9:59am.

  2. Unrelated Donor Stem Cell Transplantation

    ... states who lack a suitable sibling donor to undergo allogeneic hematopoietic progenitor cell transplantation using cells from unrelated individuals or cord blood ...

    Clinical Trial last updated 04/27/2016 - 3:18pm.

  3. Safety Study of Cord Blood Units for Stem Cell Transplants

    ... Applications (INDs) for Minimally Manipulated, Unrelated Allogeneic Placental/Umbilical Cord Blood Intended for Hematopoietic ... locally IRB-approved protocols for unrelated hematopoietic stem cell transplantation of pediatric and adult patients. Objectives ...

    Clinical Trial last updated 04/27/2016 - 2:25pm.

  4. PRO#1278: Fludarabine and Busulfan vs. Fludarabine, Busulfan and Total Body Irradiation (FLUBUTBI)

    ... and low dose total body irradiation in patients undergoing allogeneic stem cell transplantation. A study population of 80 subjects will be enrolled ...

    Clinical Trial last updated 04/29/2016 - 3:09pm.

  5. Biparental HLA Haplotype Disparate T-cell Depleted Transplants for Patients Lacking an HLACompatible Donor

    ... conditions for which CD34+ selected, T-cell depleted allogeneic hematopoietic stem cell transplantation is indicated such as: AML in 1st remission - ...

    Clinical Trial last updated 04/29/2016 - 1:59pm.

  6. A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies

    ... (DLI) on day -6 and cluster of differentiation (CD)-34+ allogeneic peripheral blood stem cell transplantation (PBSCT) on day 0. GVHD PROPHYLAXIS: Beginning on ...

    Clinical Trial last updated 04/27/2016 - 1:56pm.

  7. Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant and Cyclophosphamide, Mycophenolate Mofetil, Tacrolimus, and Sirolimus in Treating Patients With Primary Immunodeficiency Disorders or Noncancerou

    ... irradiation on day -1. TRANSPLANTATION: Patients undergo allogeneic bone marrow transplant on day 0. POST-TRANSPLANT ... Procedure: Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation Undergo allogeneic bone marrow transplantation ...

    Clinical Trial last updated 04/26/2016 - 2:09pm.

  8. Allo vs Hypomethylating/Best Supportive Care in MDS (BMT CTN 1102)

    ... one of two study arms; Arm 1: Reduced intensity conditioning allogeneic hematopoietic cell transplantation (RIC-alloHCT), Arm 2: ... Cell Transplant Bone marrow or peripheral blood stem cell transplant. The specific transplant treatment regimen will be at the ...

    Clinical Trial last updated 04/28/2016 - 10:50am.

  9. Extended Dosing With Eltrombopag for Severe Aplastic Anemia

    ... successfully treated with immunosuppressive drug regimens or allogeneic stem cell transplantation. However, 20-40% of patients are ineligible for ...

    Clinical Trial last updated 04/26/2016 - 9:36am.

  10. Safety and Efficacy of Patient's Own AD-MSC and AD-HSC Transplantation in Patients With Severe Aplastic Anemia

    ... and disease free survival of 85% to 100%, can be obtained in allogeneic blood or bone marrow stem cell transplantation using an human leukocyte antigen ( HLA ...

    Clinical Trial last updated 04/08/2016 - 11:25pm.