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  1. Azacitidine in Haploidentical Donor Hematopoietic Cell Transplantation

    ... Purpose:  Allogeneic hematopoietic cell transplantation (allo-HCT) is a potentially curative therapy for patients ... Stem cell transplant Drug: Azacitidine Other Names: Vidaza Ladakamycin ...

    Clinical Trial last updated 05/03/2016 - 11:15am.

  2. TCRαβ+/CD19+ Depleted Haploidentical HSCT + Zoledronate

    ... transplantation with a haploidentical donor peripheral blood stem cell graft depleted of TCRαβ+ cells and CD19+ cells in conjunction with ... occurring < 30 months from diagnosis, relapse after previous allogeneic hematopoietic stem cell transplant [allo-HSCT], relapse ...

    Clinical Trial last updated 04/29/2016 - 4:35pm.

  3. A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies

    ... (DLI) on day -6 and cluster of differentiation (CD)-34+ allogeneic peripheral blood stem cell transplantation (PBSCT) on day 0. GVHD PROPHYLAXIS: Beginning on ...

    Clinical Trial last updated 04/27/2016 - 1:56pm.

  4. Laboratory-Treated T Cells in Treating Patients With High-Risk Relapsed Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia Previously Treated With Donor Stem Cell Transplant

    ... of improvement (relapsed), previously treated with donor stem cell transplant . Biological therapies, such as cellular adoptive ... Analysis Correlative studies Biological: WT1-Sensitized Allogeneic T-Lymphocytes Given IV ...

    Clinical Trial last updated 04/29/2016 - 10:34am.

  5. Efficacy of Oral Azacitidine Plus Best Supportive Care as Maintenance Therapy in Subjects With Acute Myeloid Leukemia in Complete Remission (QUAZAR AML-001)

    ... of such translocations Prior bone marrow or stem cell transplantation Candidate for allogeneic bone marrow or stem cell transplant Have achieved CR/CRi ...

    Clinical Trial last updated 04/29/2016 - 8:39am.

  6. Intra-Osseous Co-Transplant of UCB and hMSC

    ... the patient's immune system from rejecting the donor's stem cells . The donated stem cells may replace the patient's immune cells ... or chloroma) Recipients of prior autologous or allogeneic transplant are eligible, as long as at least 3 months have passed ...

    Clinical Trial last updated 05/02/2016 - 11:15am.

  7. PRO#1278: Fludarabine and Busulfan vs. Fludarabine, Busulfan and Total Body Irradiation (FLUBUTBI)

    ... and low dose total body irradiation in patients undergoing allogeneic stem cell transplantation. A study population of 80 subjects will be enrolled ...

    Clinical Trial last updated 04/29/2016 - 3:09pm.

  8. Allo HSCT Using RIC for Hematological Diseases

    ... regimen followed by a related or unrelated donor stem cell infusion. The primary objective is to evaluate rates of acute ... Blood Stem Cells On day 0, patients will receive an allogeneic transplant using PBSC which are CD34+ selected as the donor graft. ...

    Clinical Trial last updated 05/02/2016 - 9:29am.

  9. Biparental HLA Haplotype Disparate T-cell Depleted Transplants for Patients Lacking an HLACompatible Donor

    ... conditions for which CD34+ selected, T-cell depleted allogeneic hematopoietic stem cell transplantation is indicated such as: AML in 1st remission - ...

    Clinical Trial last updated 04/29/2016 - 1:59pm.

  10. Allo vs Hypomethylating/Best Supportive Care in MDS (BMT CTN 1102)

    ... one of two study arms; Arm 1: Reduced intensity conditioning allogeneic hematopoietic cell transplantation (RIC-alloHCT), Arm 2: ... Cell Transplant Bone marrow or peripheral blood stem cell transplant. The specific transplant treatment regimen will be at the ...

    Clinical Trial last updated 04/28/2016 - 10:50am.