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  1. Stem Cell Transplants May Be An Option for Some Elderly MDS Patients

    ... PubMed Abstract:  Allogeneic Stem Cell Transplantations for elderly patients with Myelodysplastic Syndrome ...

    Research Review last updated 05/02/2016 - 9:33am.

  2. Administration of Donor Multi TAA-Specific T Cells for AML or MDS (ADSPAM)

    ... or has not gone away after standard treatment, including an allogeneic hematopoietic stem cell transplant (HSCT). The investigators have previously used ...

    Clinical Trial last updated 04/28/2016 - 11:40am.

  3. Expanded Access Protocol Using CD3+/CD19+ Depleted PBSC (ExpMACs)

    ... ) matched sibling donor and who are candidates for allogeneic hematopoietic stem cell transplant (HSCT). These patients have a serious or immediately ...

    Clinical Trial last updated 06/13/2016 - 1:47pm.

  4. Youmna Kfoury, PhD

    ... platform of mesenchymal stromal layers and hematopoietic stem and progenitor cells (HSPCs) using a CRISPR-Cas9 based strategy to knock ... of MDS, the only curative therapy remains that of allogeneic stem cell transplant (allo-SCT). The allo-SCT is not the ...

    Grant Recipient last updated 12/15/2016 - 12:56pm.

  5. Azacytidine Prior to in Vivo T-cell Depleted Allo Stem Cell Transplant for Patients With Myeloid Malignancies in CR

    ... conditioning for an in vivo T-cell depleted hematopoietic stem cell transplantation for high risk myeloid malignancies in complete ... regimen of fludarabine and melphalan prior to an allogeneic hematopoietic stem cell transplantation from a related or unrelated ...

    Clinical Trial last updated 05/02/2016 - 11:10am.

  6. CD8+ Memory T-Cells as Consolidative Therapy After Donor Non-myeloablative Hematopoietic Cell Transplant in Treating Patients With Leukemia or Lymphoma

    ... bone marrow , including normal blood-forming cells ( stem cells ) and cancer cells. When the healthy stem cells from a donor are ... treated with TLI and ATG reduced intensity conditioning for allogeneic transplant (any of the following AML, myelodysplastic syndrome ...

    Clinical Trial last updated 04/29/2016 - 12:36pm.

  7. Conditioning Regimen and the Transplantation of Unrelated Donor Umbilical Cord Blood in Patients With Hematologic Malignancies.

    ... of chemotherapy and radiation before giving the stem cells . However, high doses of chemotherapy and radiation can have ... within the preceding 12 months. One prior allogeneic stem cell transplant within the preceding 24 months. Prior ...

    Clinical Trial last updated 04/29/2016 - 3:51pm.

  8. Sirolimus, Cyclosporine, and Mycophenolate Mofetil in Preventing Graft-versus-Host Disease in Treating Patients With Hematologic Malignancies Undergoing Donor Peripheral Blood Stem Cell Transplant

    ... hematologic malignancies undergoing donor peripheral blood stem cell (PBSC) transplant. Giving chemotherapy and total-body ... Intervention:  Procedure: Allogeneic Hematopoietic Stem Cell Transplantation Undergo allogeneic ...

    Clinical Trial last updated 04/28/2016 - 12:07pm.

  9. GVHD Prophylaxis With Post Transplant Cyclophosphamide for Patients With Renal Insufficiency Undergoing a Conventional 8/8 HLA-matched Related or Unrelated Donor Allogeneic Hematopoietic Stem Cell Transplant

    ... GVHD is one of the most common complications of a stem cell transplant . Status:  ...

    Clinical Trial last updated 04/29/2016 - 12:40pm.

  10. Recurrent and Secondary MDS

    ... approaches, after medical treatments, and even after an allogeneic stem cell transplant . So, I think of recurrent MDS to mean progression or ...

    Interview last updated 10/24/2012 - 1:12pm.