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  1. Intensity Modulated Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant

    ... of improvement (relapsed) undergoing a second donor stem cell transplant . IMTMI is a type of radiation therapy to the bone ... high risk myelodysplastic syndrome (MDS) undergoing second allogeneic (allo)- stem cell transplant (SCT) using the same donor or ...

    Clinical Trial last updated 05/23/2016 - 2:06pm.

  2. Youmna Kfoury, PhD

    ... platform of mesenchymal stromal layers and hematopoietic stem and progenitor cells (HSPCs) using a CRISPR-Cas9 based strategy to knock ... of MDS, the only curative therapy remains that of allogeneic stem cell transplant (allo-SCT). The allo-SCT is not the ...

    Grant Recipient last updated 12/15/2016 - 12:56pm.

  3. Myeloablative Unrelated Donor Cord Blood Transplantation With T-Cell Depleted Haplo-identical Peripheral Blood Stem Cells for Patients With High Risk Hematological Malignancies

    ... this study is to find out whether the addition of blood stem cells from a close family member, when added to two units of umbilical ... FACT-approved SOP for "DONOR EVALUATION AND SELECTION FOR ALLOGENEIC TRANSPLANTATION" in the Blood and Marrow Transplant Program Manual, ...

    Clinical Trial last updated 04/29/2016 - 1:33pm.

  4. Pasireotide in Prevention of GI Toxicity

    ... side effects of the drugs received to prepare for allogeneic stem cell transplant . The study will also evaluate if Pasireotide is ...

    Clinical Trial last updated 06/06/2016 - 10:41am.

  5. A Phase III, International, Randomized, Controlled Study of Rigosertib versus Physician’s Choice of Treatment in Patients with Myelodysplastic Syndrome after Failure of a Hypomethylating Agent

    ... not eligible for, or opted not to participate in allogenic stem cell transplantation h. Off all other treatments for MDS (including ... of >30%) d.         Suitable candidate to receive allogeneic stem cell transplantation; patient is eligible for study if a ...

    Clinical Trial last updated 11/29/2016 - 8:29am.

  6. Graft-vs-host-disease (GVHD): Signs, Symptoms, and Treatment

    ... An allogeneic stem cell transplant uses blood-forming cells ( stem cells ) donated ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  7. T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus Natural Killer (NK) Cell Transplantation in Patients With Hematologic Malignancies Relapsed or Refractory Despite Previous Allogeneic Transplant

    ... improved in the group of patients who receive a T-cell replete haploidentical donor hematopoietic cell transplant (HCT) with a ... that have relapsed or are refractory after prior allogeneic transplant. Toxicity will be evaluated by the rate of transplant ... clofarabine Given on Day -9 and Day -8 (Day 0 is first stem cell infusion). Drug class: antineoplastic agent Other ...

    Clinical Trial last updated 05/03/2016 - 11:43am.

  8. Donor Stem Cell Transplant With No or Low-Intensity Chemotherapy Using Sirolimus and Treated Immune Cells to Treat Blood and Lymph Cancers

    ... and immune system often benefit from transplants of stem cells from a genetically well-matched sibling. However, severe ... of high-dose preparative chemotherapy, this study performs allogeneic transplant after low doses of chemotherapy. In an attempt to improve ...

    Clinical Trial last updated 04/28/2016 - 11:28am.

  9. A Phase II Trial of CD24Fc for Prevention of Acute Graft-versus-Host Disease Following Myeloablative Allogeneic Hematopoietic Stem Cell Transplant

    For more details on this clinical trial, including contact information, please see this trial’s listing on clinicaltrials.gov: https://clinicaltrials.gov/ct2/show/NCT02663622 ...

    Clinical Trial last updated 04/29/2016 - 11:03am.

  10. Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant

    ... undergoing unrelated donor peripheral blood stem cell transplant . Giving chemotherapy and total-body ... Intervention:  Procedure: Allogeneic Hematopoietic Stem Cell Transplantation Undergo allogeneic ...

    Clinical Trial last updated 04/28/2016 - 1:49pm.