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  1. Types

    ... French American British (FAB) Classification System The FAB system ... peripheral blood. It is now used less frequently than the WHO classification, but is included here as a reference. ...

    Topic section last updated 11/14/2016 - 1:11pm.

  2. Prognostic classification and risk assessment in myelodysplastic syndromes.

    ... model that accounts for the World Health Organization (WHO) categories, cytogenetics , transfusion dependency, and bone marrow fibrosis . This WHO classification-based Prognostic Scoring System (WPSS) is able to classify ...

    Research Article last updated 10/11/2011 - 5:58pm.

  3. Impact of the revised International Prognostic Scoring System cytogenetics and monosomal karyotype on outcome after allogeneic stem cell transplantation for myelodysplastic syndromes and secondary acute myeloid leukemia evolving from myelodysplastic syndr

    ... International Prognostic Scoring System -cytogenetic classification on outcome after allogeneic stem cell transplantation in ... syndromes or secondary acute myeloid leukemia who were reported to the European Society for Blood and Marrow Transplantation ...

    Research Article last updated 03/02/2015 - 2:46pm.

  4. Validation of WHO classification-based Prognostic Scoring System (WPSS) for myelodysplastic syndromes and comparison with the revised International Prognostic Scoring System (IPSS-R). A study of the International Working Group for Prognosis in Myelodyspla

    ... for myelodysplastic syndromes (MDS). We refined the WHO-classification based Prognostic Scoring System (WPSS) by determining the ...

    Research Article last updated 03/03/2015 - 12:07pm.

  5. Improved risk stratification by the integration of the revised International Prognostic Scoring System with the Myelodysplastic Syndromes Comorbidity Index

    ... Risk Model Score (MDAS), World Health Organisation (WHO)-classification based Prognostic Scoring System (WPSS), refined WPSS (WPSS-R), ...

    Research Article last updated 01/20/2015 - 1:12pm.

  6. Study of Vadastuximab Talirine (SGN-CD33A; 33A) in Combination With Azacitidine in Patients With Previously Untreated Higher Risk MDS

    ... confirmed MDS according to the World Health Organization (WHO) 2008 classification. Previously untreated for Myelodysplastic Syndrome (MDS) ...

    Clinical Trial last updated 06/19/2017 - 2:44pm.

  7. IDH mutations are closely associated with mutations of DNMT3A, ASXL1 and SRSF2 in patients with myelodysplastic syndromes and are stable during disease evolution.

    ... identified in 4.6% of 477 patients with MDS based on the FAB classification and in 2.2 % of 368 patients based on the 2008 WHO classification. IDH mutations were closely associated with older age, ... lower-risk MDS, based on international prognosis scoring system (IPSS), FAB classification, WHO classification, or revised IPSS (all ...

    Research Article last updated 10/22/2013 - 12:48pm.

  8. Methylation of the p73 gene in patients with myelodysplastic syndromes: correlations with apoptosis and prognosis

    ... and the marrow blast levels (p  =  0.037) and the WHO classification (p  =  0.016). The frequency of p73 methylation was ...

    Research Article last updated 11/05/2012 - 10:10am.

  9. Coalesced Multicentric Analysis of 2,351 Patients With Myelodysplastic Syndromes Indicates an Underestimation of Poor-Risk Cytogenetics of Myelodysplastic Syndromes in the International Prognostic Scoring System.

    ... (IPSS) remains the most commonly used system for risk classification in myelodysplastic syndromes (MDSs). The IPSS gives more ... PATIENTS AND METHODS In total, 2,351 patients with MDS who have records in the German-Austrian and the MD Anderson Cancer Center ...

    Research Article last updated 10/11/2011 - 5:58pm.

  10. Myelodysplastic syndromes: an update on molecular pathology.

    ... neoplasms according to the World Health Organization (WHO) classification system for haematological cancers. Given their cytological and ...

    Research Article last updated 10/11/2011 - 5:58pm.