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  1. Value of allogeneic versus autologous stem cell transplantation and chemotherapy in patients with myelodysplastic syndromes and secondary acute myeloid leukemia. Final results of a prospective randomized European Intergroup Trial.

    ... Primary Author:  de Witte T Author(s):  de Witte T, ... BACKGROUND: Allogeneic stem cell transplantation is usually considered the only curative treatment option ...

    Research Article last updated 10/11/2011 - 5:58pm.

  2. New positive results for GVHD treatment

    ... a common and serious complication of a type of stem cell transplant , findings from a small clinical trial show. ... the activity of a similar protein, ITK, on B cells and T cells. Several studies have shown that improper activation of both of these ...

    Article last updated 01/12/2017 - 11:10am.

  3. Resources to Help

    ... the needs of patients facing a  bone marrow , blood stem cell or umbilical  cord blood transplant . In addition to high-quality ... the standard advanced care planning documents don’t meet all the needs of younger patients. This study found that adolescents and ...

    Topic section last updated 10/20/2017 - 10:23am.

  4. Allogeneic stem cell transplantation for myelodysplastic syndromes with bone marrow fibrosis.

    ... Author(s):  Kröger N, Zabelina T, van Biezen A, Brand R, Niederwieser D, Martino R, Lim ZY, Onida F, Schmid C, ... poor outcome, but whether the outcome after allogeneic stem cell transplantation is related to the degree of bone marrow fibrosis is ...

    Research Article last updated 07/28/2014 - 8:21am.

  5. Erythropoietin administration is associated with improved T-cell properties in patients with myelodysplastic syndromes

    ... of recombinant human erythropoietin (rHuEPO) on T cell (CD4+, CD8+ and CD4+CD25+) number and function in MDS patients. ...

    Research Article last updated 12/09/2016 - 3:05pm.

  6. A novel histone deacetylase inhibitor Chidamide induces G0/G1 arrest and apoptosis in myelodysplastic syndromes

    ... been used in several clinical trials such as peripheral T cell lymphoma (PTCL). Here we demonstrate that Chidamide was able to ...

    Research Article last updated 11/02/2016 - 9:39am.

  7. Clone of Patients

    ...

    Page last updated 03/14/2016 - 6:05pm.

  8. Safety Study of Gene Modified Donor T-cells Following TCR Alpha Beta Depleted Stem Cell Transplant

    ... pediatric patients with malignant or non-malignant blood cell disorders who are having a blood stem cell transplant depleted of T cell receptor (TCR) alfa and beta cells that comes from a partially ...

    Clinical Trial last updated 04/28/2016 - 12:39pm.

  9. On the horizon: Man-made bone marrow

    ... with non-malignant bone marrow diseases, where there aren’t any cancerous cells that need to be eliminated. Examples include aplastic ... marrow stem cells. That would have useful applications for cell transplantations in the clinic,” Varghese said. ...

    Article last updated 05/09/2017 - 10:41am.

  10. Association between donor leukocyte telomere length and survival after unrelated allogeneic hematopoietic cell transplantation for severe aplastic anemia

    ... Author(s):  Gadalla SM, Wang T, Haagenson M, Spellman SR, Lee SJ, Williams KM, Wong JY, De Vivo I, Savage SA ... after unrelated donor allogeneic hematopoietic cell transplantation (HCT) for patients with severe aplastic anemia . ...

    Research Article last updated 03/03/2015 - 11:48am.