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  1. Transplant Experience Amplifies Her Desire for Research Career

    ... I found my hair scattered across my bed. I couldn’t eat because I constantly threw up, and I lost my ability to taste as all my ... old children I had ever met. He was battling sickle cell anemia, and had a transplant from an unrelated donor . The hospital ...

    Patient Chronicle last updated 04/26/2018 - 12:47pm.

  2. Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant Diseases

    ... study is to determine a safe dose of BPX-501 gene modified T cells infused after a haplo-identical stem cell transplant to facilitate engraftment and the safety of AP1903 ...

    Clinical Trial last updated 06/13/2016 - 1:54pm.

  3. Maintenance Low Dose 5'-Azacitidine Post T Cell Depleted Allogeneic Stem Cell Transplantation for Patients With Myelodysplastic Syndrome and Acute Myelogenous Leukemia With High Risk for Post-Transplant Relapse

    ... lower the risk of the disease coming back after a stem cell transplant in patients with MDS and AML. This study will also be ... between days 60-120 post TCD allogeneic hematopoietic stem cell transplant and up to a year post-transplant or until there is a toxicity ...

    Clinical Trial last updated 04/27/2016 - 1:19pm.

  4. T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus Natural Killer (NK) Cell Transplantation in Patients With Hematologic Malignancies Relapsed or Refractory Despite Previous Allogeneic Transplant

    ... improved in the group of patients who receive a T-cell replete haploidentical donor hematopoietic cell transplant (HCT) with a ... and study comprehensively immune reconstitution following T-cell replete haploidentical transplantation. ...

    Clinical Trial last updated 05/03/2016 - 11:43am.

  5. Transplantation


    Page last updated 01/20/2015 - 4:45pm.

  6. Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts for the Prevention of GVHD in Children

    ... This phase II trial studies how well T cell depleted donor peripheral blood stem cell transplant works in ...

    Clinical Trial last updated 06/13/2016 - 2:29pm.

  7. Cardiac iron overload in chronically transfused patients with thalassemia, sickle cell anemia, or myelodysplastic syndrome

    ... Bouabdallah K, Cavazzana M, Chauzit E, Baptiste A, Lefebvre T, Puy H, Elie C, Karim Z, Ernst O, Rose C ... myelodysplastic syndromes (MDS). In patients with sickle cell anemia (SCA), iron does not seem to deposit quickly in the heart. ...

    Research Article last updated 03/22/2017 - 10:46am.

  8. A Remarkable Response in a Clinical Trial

    ... (MDS), a disease that has no cure except for a stem cell transplant . Because I was in my mid-70s, a bone marrow transplant wasn’t the best option. At the time of the diagnosis, my spouse, Jim, and I had ...

    Patient Chronicle last updated 04/26/2018 - 12:46pm.

  9. I’m working through aplastic anemia – my son helps me keep focused.

    ... started bleeding. I hoped this would stop, but that didn’t happen. Finally, when I was attending a local football game, one side of my ... is a half-matched donor. My approval for a stem cell transplant at National Institutes of Health (NIH) came recently. I ...

    Patient Chronicle last updated 01/11/2018 - 9:55am.

  10. Isabel Mérida, PhD

    ... bone marrow by overactive immune system blood cells called T-cells. Healthy T cells are "trained" to recognize and destroy exclusively ... functions as a brake limiting immune-dependent T cell attack. We recently found that when mice are genetically modified to ...

    Grant Recipient last updated 07/05/2018 - 11:17am.