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  1. Research Overview - Recent Past Progress and Projections for the Near-Term

    ... is that unlike solid tumors and leukemia, where there are cell lines that are propagated from the disease, we do not have reliable ... an enzyme called pyruvate dehydrogenase. This wasn’t just in MDS, but in all advanced hematologic malignancies. In this study, ...

    Interview last updated 02/10/2014 - 9:40am.

  2. Donor Umbilical Cord Blood Transplant With or Without Ex-vivo Expanded Cord Blood Progenitor Cells in Treating Patients With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, or Myelodysplastic Syndromes

    ... monohydrate CTX CYCLO-cell Cycloblastin Cycloblastine Cyclophospham Cyclophosphamid ... Ex Vivo-Expanded Cord Blood Progenitor Cell Infusion Given IV Drug: Fludarabine Phosphate Given IV Other ... T 586 Other: Laboratory Biomarker Analysis Correlative studies Drug: ...

    Clinical Trial last updated 04/27/2016 - 1:17pm.

  3. MDS and MDS/MPN: Past, Present, and Future 2014 American Society of Hematology (ASH) Satellite Symposium Summary for Patients and Families

    ... advanced techniques to study genes and chromosomes don’t give enough information to find out what type of MDS or MDS/MPN a patient ... silenced genes). But some patients with MDS don’t respond to HMAs, and most patients who do respond eventually have a ... Can We Cure Them? The Role of Hematopoietic Stem Cell Transplantation in MDS/MPN.   Treatments for MDS/MPN are ...

    Page last updated 03/13/2015 - 5:00pm.

  4. Aaron T. Gerds, MD, MS

    ... (CMML), with a special emphasis on allogeneic hematopoietic cell transplantation. Dr. Gerds is also an active member of the American ...

    Bio last updated 03/11/2016 - 1:41pm.

  5. Veteran Patients

    ... The fact that an exposure is remote in time doesn’t mean it can’t contribute to MDS. A major  epidemiological study ... the 1960s or 1970s, that DNA injury in a bone marrow cell could have made it more likely that MDS would develop later on as a result ...

    Topic section last updated 03/25/2016 - 11:56am.

  6. What are the treatments for PNH?

    ... to do nothing but monitor your blood counts if they aren't too low and your symptoms aren't too bad. Supportive Care : ... , the destruction of red blood cells. Bone marrow/stem cell transplantation (BMT/SCT):  A procedure that replace your unhealthy ...

    FAQ last updated 03/15/2016 - 11:32pm.

  7. What are the treatments for MDS?

    ... to do nothing but monitor you if your blood counts aren't too low and your symptoms aren't too bad. Supportive care : ... using drugs that kill abnormal cells. Bone marrow/stem cell transplantation (BMT/SCT): A procedure that replaces your unhealthy ...

    FAQ last updated 03/15/2016 - 11:31pm.

  8. Blood Transfusions

    Page last updated 11/19/2014 - 2:46pm.

  9. Pediatric MDS

    ... rst spotted as cytopenias (low blood counts). It’s a stem cell disorder in the bone marrow that results in disturbances  in ... anemia with ringed sideroblasts (RARS), that don’t occur in children. Another interesting point is that one-third to one-half of ...

    Interview last updated 10/24/2012 - 1:31pm.

  10. Making the Most of Office Visits with Your Specialist

    ... one starts. It is ok for a patient to say “I don’t understand. Will you please rephrase or restate the diagnosis in a different ... acute myeloid leukemia (AML), and allogeneic hematopoietic cell transplant. Dr. Cogle leads a research laboratory that studies the biology ...

    Interview last updated 10/14/2015 - 9:05am.