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  1. Fludarabine/Clofarabine/Busulfan Combined With SAHA in Acute Leukemia

    ... course of induction and with favorable cytogenetics [t(8;21, inv 16, or t(15;17)] and/or molecular profile (NPM1). Prior ... Acid MSK-390 Zolinza Procedure: Stem Cell Infusion (SCT) Stem cell infusion on Day 0. Drug: ...

    Clinical Trial last updated 06/06/2016 - 11:07am.

  2. Aplastic Anemia: Why Treatments Work and Why They Don't

    ... Immunosuppressive therapy and stem cell transplantation are the main treatment options for aplastic anemia ... Aplastic Anemia: Why Treatments Work and Why They Don't/Aplastic Anemia: Why Treatments Work and Why They Don't ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  3. Aplastic Anemia: Why Treatments Work and Why They Don't

    ... Immunosuppressive therapy and stem cell transplantation are the main treatment options for aplastic anemia ... Aplastic Anemia: Why Treatments Work and Why They Don't ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  4. Resistance to Hypomethylating Agents in the Treatment of MDS

    ... applies mostly to higher-risk MDS patients, because we don’t usually treat lower-risk category patients upfront with these agents. ... effect by inhibiting protein synthesis. Both drugs enter the cell and require a special enzyme to cause phosphorylation that results in its ...

    Interview last updated 06/17/2014 - 9:15am.

  5. Autoreactive T Cells From Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Specifically Recognize Glycosyl- Phosphatidyl-Inositol (GPI)

    ... PNH seems to be a different type of disease. Here the PNH cell is not attacked because of a molecule it has, but rather, because of ... proteins (such as CD55 and CD59) normally prevent the red cell from being broken down by complement proteins. In a way, PNH could also be ...

    Research Review last updated 05/02/2016 - 9:26am.

  6. Conferences, Webinars and Webcasts

    ... -Judy  I now know this disease shouldn’t stop me from living life as best I can. – Evelyn   Webinars & ...   Caregivers   Clinical Trials   Stem Cell Transplantation   Living Well   Nutrition   ...

    Page last updated 09/30/2014 - 11:50am.

  7. MDS - Basics

    ... ? Bone marrow failure happens when the marrow doesn't produce enough red cells, white cells or platelets, or the blood cells that ... MDS have two things in common: They have a low blood cell count for at least one blood cell type. This is called a cytopenia ...

    Topic section last updated 04/06/2016 - 1:22pm.

  8. Clone of Myelodysplastic Syndromes (MDS)

    ... ? Bone marrow failure happens when the marrow doesn't produce enough red cells, white cells or platelets, or the blood cells that ... MDS have two things in common: They have a low blood cell count for at least one blood cell type. This is called a cytopenia . ...

    Page last updated 04/05/2016 - 3:56pm.

  9. Interviews with the Experts MDS Genomics: Providing ‘Street View’ Directions of Disease

    ... for any study of chromosomes , genes, and DNA in a cell. “Genetics” is a more specific term that pertains to the study of just ... There are situations where patients and doctors aren’t completely sure if the patient has MDS or not. The patient may have low blood ...

    Interview last updated 09/23/2014 - 9:30am.

  10. Donor Umbilical Cord Blood Transplant With or Without Ex-vivo Expanded Cord Blood Progenitor Cells in Treating Patients With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, or Myelodysplastic Syndromes

    ... monohydrate CTX CYCLO-cell Cycloblastin Cycloblastine Cyclophospham Cyclophosphamid ... Ex Vivo-Expanded Cord Blood Progenitor Cell Infusion Given IV Drug: Fludarabine Phosphate Given IV Other ... T 586 Other: Laboratory Biomarker Analysis Correlative studies Drug: ...

    Clinical Trial last updated 04/27/2016 - 1:17pm.