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  1. Fatigue in Bone Marrow Failure Diseases

    ... of data yet looking at fatigue in the diseases that aren’t cancer. However, with the help of AA&MDSIF we recently conducted a study ... For example, are chemotherapy , radiation and stem cell transplants all suspect, along with non-treatment sources of fatigue? ...

    Interview last updated 01/06/2017 - 2:22pm.

  2. Understanding Prognosis in MDS

    ... may suggest a more risky therapy, such as a stem cell transplant , be tried. A better prognosis that indicates a longer life ... and decitabine (Dacogen®)—and IPSS doesn’t take the effect of these into account. Another drawback is that it is not ...

    Interview last updated 05/02/2012 - 4:36pm.

  3. Ron Duncan, Texas Walk Committee

    ... I went again in March 2005, I was informed that I couldn't give  and actually really needed a transfusion. Eventually I was diagnosed with pure red cell aplasia, PRCA, a very rare condition where I don't make red blood cells. I ...

    Patient Chronicle last updated 01/06/2017 - 10:52am.

  4. Interviews with the Experts Comorbidities: When Other Medical Conditions Affect MDS Treatment

    ... cases this particular comorbid condition can even help: red cell growth factors like darbepoetin (Aranesp®) or epoetin (Procrit®) can ... So in many cases, patients with serious comorbidities aren’t eligible to participate in clinical trials. But that restrictive clinical ...

    Interview last updated 11/17/2014 - 9:31am.

  5. AA&MDSIF announces PNH grant awards

    ... hemolytic anemia that results from the loss of cell surface complement regulators. These patients have hemolytic anemia, risk ... functional effects of the PIG-A mutation in CD34+ cells and T- cells shared by PNH, MDS and aplastic anemia patients. The goal is to ...

    Article last updated 12/14/2016 - 11:41am.

  6. Overlap Syndromes: When PNH Appears with Aplastic Anemia

    ... hemolysis .  In patients a with large PNH red cell population who need aplastic anemia treatment, one thing to do is give ... can be seen in PNH or aplastic anemia, but it doesn’t secure a diagnosis of MDS. ...

    Interview last updated 04/15/2015 - 9:39am.

  7. Biting into the Elephant

    ... low. They told us there was something wrong, but they didn’t know what it was. Referring us to a hematologist / oncologist , ... azacitidine (Vidaza®) treatment followed by a stem cell transplant . I received the gift of life from my brother Neal on ...

    Patient Chronicle last updated 06/27/2016 - 2:22pm.

  8. Myelofibrosis (MF)

    ... and chronic inflammation. If the marrow is scarred, it can’t produce blood cells correctly or perform its normal functions. As a result, ... myelofibrosis than younger people. Having another blood cell disorder, like essential thrombocythemia or polycythemia vera, as these ...

    Topic section last updated 07/07/2016 - 3:16pm.

  9. Eltrombopag With Standard Immunosuppression for Severe Aplastic Anemia

    ... understood, but incomplete elimination of auto-reactive T cells and insufficient stem cell reserve are both possible. Furthermore, 10-15% of SAA patients treated ...

    Clinical Trial last updated 04/25/2016 - 2:47pm.

  10. Nonmyeloablative Haploidentical Transplant Followed by MLN9708

    ... strategies to augment the well documented effect of NK cell alloreactivity seen in HLA -mismatched transplantation. These ... receive a nonmyeloablative haploidentical transplant using a T-cell replete allograft and post-transplant cyclophosphamide as ...

    Clinical Trial last updated 04/29/2016 - 1:05pm.