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  1. FAQs

    ... families. Just click on the question to view the answer. Don't see the answer to your question here? Send your question to our patient ... MDS, you must have low blood counts for at least one blood cell type and your blood cells must look abnormal under a microscope. Doctors ...

    Topic section last updated 03/02/2016 - 11:43am.

  2. Special Issues for People with PNH

    ... these things, it's a good idea to: Get a red blood cell count Get treatment for your anemia (blood transfusions or ... weigh the risks and benefits of getting a flu shot. Don’t forget to ask whether your family members and others in close contact with ...

    Page last updated 01/20/2015 - 4:59pm.

  3. Sicheng Wen, MD, PhD

    ... Reversal of aplastic anemia by mensenchymal stem cell-derived extracellular vesicles Original Research ... Aplastic anemia is a blood disorder where the body doesn't make enough blood cells. Marrow transplantation, antithymocyte globulin ...

    Grant Recipient last updated 09/16/2016 - 2:51pm.

  4. Myelofibrosis (MF)

    ... and chronic inflammation. If the marrow is scarred, it can’t produce blood cells correctly or perform its normal functions. As a result, ... myelofibrosis than younger people. Having another blood cell disorder, like essential thrombocythemia or polycythemia vera, as these ...

    Topic section last updated 07/07/2016 - 3:16pm.

  5. Research Retrospective for AA&MDSIF 30th Anniversary - Dr. Neal Young

    ... readily available to most patients, changes in red blood cell transfusion methods have decreased the problem of alloimmunization, ... of the underlying pathophysiology , we really don’t’ understand it in detail. So, empirically, horse ATG remains our best ...

    Interview last updated 05/08/2013 - 2:51pm.

  6. North American Pediatric Aplastic Anemia Consortium Symposium

    ... to show mild dysplasia and patchy areas of red blood cell , or erythroid, precursors. However, in the absence of an MDS defining ... graft rejection, which is problematic for patients who don’t respond to IST. As donor matching and supportive care within hematopoietic ...

    Page last updated 10/31/2013 - 4:06pm.

  7. Biting into the Elephant

    ... low. They told us there was something wrong, but they didn’t know what it was. Referring us to a hematologist / oncologist , ... azacitidine (Vidaza®) treatment followed by a stem cell transplant . I received the gift of life from my brother Neal on ...

    Patient Chronicle last updated 06/27/2016 - 2:22pm.

  8. Eltrombopag: Recent Discoveries on Potential New Applications for Aplastic Anemia

    ... in some patients, but also improve white and red blood cell counts. This was a surprising finding, as the drug was really ... trials for aplastic anemia? Originally we weren't that hopeful that eltrombopag would be useful in aplastic anemia, because the ...

    Interview last updated 02/14/2014 - 2:01pm.

  9. Understanding Prognosis in MDS

    ... may suggest a more risky therapy, such as a stem cell transplant , be tried. A better prognosis that indicates a longer life ... and decitabine (Dacogen®)—and IPSS doesn’t take the effect of these into account. Another drawback is that it is not ...

    Interview last updated 05/02/2012 - 4:36pm.

  10. Eltrombopag With Standard Immunosuppression for Severe Aplastic Anemia

    ... understood, but incomplete elimination of auto-reactive T cells and insufficient stem cell reserve are both possible. Furthermore, 10-15% of SAA patients treated ...

    Clinical Trial last updated 04/25/2016 - 2:47pm.