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  1. Diagnosis

    ... uses a number of methods to measure how many of each blood cell type are in your blood sample. If the CBC shows a low number of red blood ... that are not normal. These abnormal looking cells don’t work right, and this can lead to anemia. ...

    Topic section last updated 04/19/2016 - 3:35pm.

  2. Role of microRNAs in Aplastic Anemia

    ... M.D.   Abstract 2940: Altered microRNAs in T cells from Patients with Acquired Aplastic Anemia MicroRNAs ... from healthy people and from patients with MDS or sickle cell disease. Key findings: miRNAs were downregulated, meaning that ...

    Research Review last updated 05/02/2016 - 9:15am.

  3. Myelodysplastic Syndromes and autoimmune disorders: Cause or consequence?

    ... cytopenias in MDS patients. For instance, deregulated T cell immunity which leads to downstream inflammatory responses can induce ...

    Research Review last updated 05/02/2016 - 9:18am.

  4. Transplantation Update

    ... toxicity from the regimens used to prepare patients for stem cell transplants regardless of who the donor is or the source of stem cells ... The results showed that this can work, but we can’t completely omit cyclophosphamide because there was failure of engraftment ...

    Interview last updated 05/14/2015 - 2:42pm.

  5. Disease Won't Run My Life

    ... Jersey and I walked in while he parked the car.  I didn’t know I wouldn’t be leaving for five more days. Once I explained my ... but my very low blood counts continued for all three cell lines. The “aplastic crisis” morphed into severe aplastic anemia which ...

    Patient Chronicle last updated 05/10/2016 - 3:36pm.

  6. Sicheng Wen, MD, PhD

    ... Reversal of aplastic anemia by mensenchymal stem cell-derived extracellular vesicles Original Research ... Aplastic anemia is a blood disorder where the body doesn't make enough blood cells. Marrow transplantation, antithymocyte globulin ...

    Grant Recipient last updated 09/16/2016 - 2:51pm.

  7. Immunosuppressive Therapy

    ... works by killing specific cells in your immune system called T-lymphocytes — the cells that are attacking bone marrow stem cells ... prevents T-lymphocytes, a type of white blood cell , from becoming active. Once the T-lymphocytes are turned off by the ...

    Topic section last updated 04/01/2016 - 2:24pm.

  8. FAQs

    ... families. Just click on the question to view the answer. Don't see the answer to your question here? Send your question to our patient ... MDS, you must have low blood counts for at least one blood cell type and your blood cells must look abnormal under a microscope. Doctors ...

    Topic section last updated 03/02/2016 - 11:43am.

  9. Special Issues for People with PNH

    ... these things, it's a good idea to: Get a red blood cell count Get treatment for your anemia (blood transfusions or ... weigh the risks and benefits of getting a flu shot. Don’t forget to ask whether your family members and others in close contact with ...

    Page last updated 01/20/2015 - 4:59pm.

  10. Myelofibrosis (MF)

    ... and chronic inflammation. If the marrow is scarred, it can’t produce blood cells correctly or perform its normal functions. As a result, ... myelofibrosis than younger people. Having another blood cell disorder, like essential thrombocythemia or polycythemia vera, as these ...

    Topic section last updated 07/07/2016 - 3:16pm.