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  1. Conditioning Regimen and the Transplantation of Unrelated Donor Umbilical Cord Blood in Patients With Hematologic Malignancies.

    ... disorder; Therapy related AML; White cell count at presentation > 100,000; Presence of extramedullary leukemia ... Presence of a high-risk cytogenetic abnormality such as t(9;22), t(1;19), t(4;11) or other MLL rearrangements (11q23)or other high-risk ...

    Clinical Trial last updated 04/29/2016 - 3:51pm.

  2. Phase I/II MAHCT w/ TCell Depleted Graft w/ Simultaneous Infusion Conventional and Regulatory T Cell

    ... undergoing allogeneic myeloablative (MA) HCT with a T cell depleted graft, the infusion of naturally occurring regulatory T cells ...

    Clinical Trial last updated 05/09/2016 - 3:58pm.

  3. Youmna Kfoury, PhD

    ... 1-    Confirm preliminary data on the human mesenchymal cell population corresponding to the mouse Osterix+ cells in the bone ... L., Kempton, H.R., Dahlman, J.E., Parnas, O., Eisenhaure, T.M., Jovanovic, M., et al. (2014). CRISPR-Cas9 knockin mice for genome editing ...

    Grant Recipient last updated 12/15/2016 - 12:56pm.

  4. Exercise

    ... within the last year and/or if your white blood cell count is low If you are undergoing radiation therapy, avoid ... be part of our daily lives and it should be fun. It doesn’t have to be high intensity or inconvenient. Disregard the old saying of “no ...

    Page last updated 12/28/2016 - 12:06pm.

  5. Nutrition

    ... If you have a very low neutrophil count (low white blood cell count), ask your doctor about a special diet called a neutropenic ... including potatoes, applesauce or rice. If you aren’t eating these foods, then take Benefiber or similar product:  2-3 teaspoons ...

    Page last updated 03/07/2017 - 3:19pm.

  6. Kate MacNamara, PhD

    ... are known to contribute to pathology, yet exactly how stem cell function is compromised by these factors is not clear and remains an ... striking because we observed similar numbers of activated T lymphocytes and similar levels of pro-inflammatory cytokines, including ...

    Grant Recipient last updated 06/08/2017 - 10:43am.

  7. Joseph Oved, MD

    ... model proposes that the immune system and specifically T cells are responsible for this destruction. Pediatric and adult aplastic ... patients with aplastic anemia have a tendency to develop cell populations that are predisposed to myelodysplastic syndrome and leukemia. ...

    Grant Recipient last updated 06/08/2017 - 10:40am.

  8. GVHD Prophylaxis With Post Transplant Cyclophosphamide for Patients With Renal Insufficiency Undergoing a Conventional 8/8 HLA-matched Related or Unrelated Donor Allogeneic Hematopoietic Stem Cell Transplant

    ... GVHD is one of the most common complications of a stem cell transplant . Status:  ... in 1st remission with 'good risk' cytogenetic features (i.e. t(8;21), t(15;17), inv 16). Secondary AML ALL/LL in 1st remission with ...

    Clinical Trial last updated 04/29/2016 - 12:40pm.

  9. Laboratory-Treated T Cells in Treating Patients With High-Risk Relapsed Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia Previously Treated With Donor Stem Cell Transplant

    ... I/II trial studies the side effects of laboratory-treated T cells and to see how well they work in treating patients with high-risk acute ... (relapsed), previously treated with donor stem cell transplant . Biological therapies, such as cellular adoptive ...

    Clinical Trial last updated 04/29/2016 - 10:34am.

  10. Transplantation Update

    ... toxicity from the regimens used to prepare patients for stem cell transplants regardless of who the donor is or the source of stem cells ... The results showed that this can work, but we can’t completely omit cyclophosphamide because there was failure of engraftment ...

    Interview last updated 05/14/2015 - 2:42pm.