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  1. Total Marrow and Lymphoid Irradiation and Chemotherapy Before Donor Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Leukemia

    ... together with chemotherapy before donor stem cell transplant in treating patients with myelodysplasticsyndrome or acute ... is, instead of applying radiation to the whole body. Stem cell transplants use high doses of chemotherapy and radiation therapy, such as ... T 586 Other: Laboratory Biomarker Analysis Correlative studies Drug: ...

    Clinical Trial last updated 04/29/2016 - 12:58pm.

  2. Lower-Risk MDS: Diagnosis and Treatment Options

    ... primary problem. Is it anemia , or a low white blood cell count, or is it a low platelet count?   Anemia is the most frequent ... usually given with cyclosporine , which is a T cell suppressor. Some MDS patients respond to this treatment. The major ...

    Interview last updated 05/18/2012 - 1:28pm.

  3. Chronic Myeloproliferative Neoplasms (MPN)

    ... different types of MPN are generally defined by the type of cell which is most affected. They include: Chronic myelogenous leukemia ... many cells. In myelodysplastic syndromes, blood cells don’t mature and begin to fill the bone marrow. Certain types of ...

    Topic section last updated 07/07/2016 - 3:19pm.

  4. Kathryn (Kate) Bauer, Retired MDS Patient Living Life to the Fullest Since Transplant

    ... syndromes (MDS). My first thought was, "I can't even spell it!"  The stage was Refractory Anemia with Excess ... and also had the first of about 50 red blood cell transfusions. Ten days later, a day after my 59th birthday, I bit a ...

    Patient Chronicle last updated 07/23/2015 - 9:38am.

  5. Duane Draper builds supportive community to help him with MDS and bone marrow transplant

    ... father of two grown children was asymptomatic and didn’t even realize that there was a problem with his health. Though he had been ... as well. Procrit shots increased his red blood cell production while he explored his options for treatment. A ...

    Patient Chronicle last updated 09/09/2014 - 10:02am.

  6. Conditioning Regimen and the Transplantation of Unrelated Donor Umbilical Cord Blood in Patients With Hematologic Malignancies.

    ... disorder; Therapy related AML; White cell count at presentation > 100,000; Presence of extramedullary leukemia ... Presence of a high-risk cytogenetic abnormality such as t(9;22), t(1;19), t(4;11) or other MLL rearrangements (11q23)or other high-risk ...

    Clinical Trial last updated 04/29/2016 - 3:51pm.

  7. Phase I/II MAHCT w/ TCell Depleted Graft w/ Simultaneous Infusion Conventional and Regulatory T Cell

    ... undergoing allogeneic myeloablative (MA) HCT with a T cell depleted graft, the infusion of naturally occurring regulatory T cells ...

    Clinical Trial last updated 05/09/2016 - 3:58pm.

  8. Overlap Syndromes: When PNH Appears with Aplastic Anemia or MDS

    ... (scarring in the marrow), a chronically high white blood cell or platelet count, especially if they have the JAK2 ... not generally develop after an MDS diagnosis, if they didn’t already have PNH to begin with. Are there any areas where the boundaries ...

    Interview last updated 05/14/2015 - 1:53pm.

  9. A Phase III, International, Randomized, Controlled Study of Rigosertib versus Physician’s Choice of Treatment in Patients with Myelodysplastic Syndrome after Failure of a Hypomethylating Agent

    ... anemia with excess blasts in transformation (RAEB t) based on the French-American-British (FAB) classification (Appendix 3). The ... eligible for, or opted not to participate in allogenic stem cell transplantation h. Off all other treatments for MDS (including AZA ...

    Clinical Trial last updated 11/29/2016 - 8:29am.

  10. San Diego Family Takes Action for Awareness

    ... noted that his blood counts were low and, while he didn’t rule out that the spider bite might have affected the counts, there was a ... he no longer needed transfusions. A search for a stem cell donor had been started prior to this treatment. Because David is ...

    Patient Chronicle last updated 10/26/2016 - 11:42am.