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  1. Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant

    ... undergoing unrelated donor peripheral blood stem cell transplant . Giving chemotherapy and total-body irradiation before a donor peripheral blood stem cell transplant (PBSCT) helps stop the growth of cancer cells. It may also stop ... T 586 Drug: Mycophenolate Mofetil Given PO Other ...

    Clinical Trial last updated 04/28/2016 - 1:49pm.

  2. Pasireotide in Prevention of GI Toxicity

    ... of the drugs received to prepare for allogeneic stem cell transplant . The study will also evaluate if Pasireotide is effective ... remission, with high risk being defined by the presence of t(4;11) or t(9;22), or those presenting with extreme hyperleukocytosis or ...

    Clinical Trial last updated 06/06/2016 - 10:41am.

  3. Myelodysplastic Syndromes (MDS)

    ... ? Bone marrow failure happens when the marrow doesn't produce enough red cells, white cells or platelets, or the blood cells that ... MDS have two things in common: They have a low blood cell count for at least one blood cell type. This is called a cytopenia . ...

    Page last updated 02/27/2017 - 7:36am.

  4. BMT Meant 'It Could Finally Be Over '

    ... and repeated only one thought - “just finish”. I didn’t think about winning. I didn’t think about beating any records or trying to ... 2013, the beginning of my senior year, my red blood cell counts dropped dramatically. I had to get my first red blood cell ...

    Patient Chronicle last updated 05/10/2016 - 3:28pm.

  5. A Phase III, International, Randomized, Controlled Study of Rigosertib versus Physician’s Choice of Treatment in Patients with Myelodysplastic Syndrome after Failure of a Hypomethylating Agent

    ... anemia with excess blasts in transformation (RAEB t) based on the French-American-British (FAB) classification (Appendix 3). The ... eligible for, or opted not to participate in allogenic stem cell transplantation h. Off all other treatments for MDS (including AZA ...

    Clinical Trial last updated 11/29/2016 - 8:29am.

  6. Chronic Myeloproliferative Neoplasms (MPN)

    ... different types of MPN are generally defined by the type of cell which is most affected. They include: Chronic myelogenous leukemia ... many cells. In myelodysplastic syndromes, blood cells don’t mature and begin to fill the bone marrow. Certain types of ...

    Topic section last updated 07/07/2016 - 3:19pm.

  7. Total Marrow and Lymphoid Irradiation and Chemotherapy Before Donor Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Leukemia

    ... together with chemotherapy before donor stem cell transplant in treating patients with myelodysplasticsyndrome or acute ... is, instead of applying radiation to the whole body. Stem cell transplants use high doses of chemotherapy and radiation therapy, such as ... T 586 Other: Laboratory Biomarker Analysis Correlative studies Drug: ...

    Clinical Trial last updated 04/29/2016 - 12:58pm.

  8. My MDS Diagnosis and Progression of Treatment

    ... getting a burning feeling in my left foot.  Because it wasn't that bad I let it go, but by the holidays of that year, I could barely put my ... Unfortunately, this drug also lowers my red blood cell counts and my hemoglobin along with the platelets. I have lab ...

    Patient Chronicle last updated 12/15/2016 - 11:19am.

  9. San Diego Family Takes Action for Awareness

    ... noted that his blood counts were low and, while he didn’t rule out that the spider bite might have affected the counts, there was a ... he no longer needed transfusions. A search for a stem cell donor had been started prior to this treatment. Because David is ...

    Patient Chronicle last updated 10/26/2016 - 11:42am.

  10. Dr. Kasiani Myers: Acquired and Inheirited Bone Marrow Failure

    ... cells . Usually acquired aplastic anemia patients don’t have other issues associated with it, but inherited aplastic anemia patients ... are not. The common treatment they share is bone marrow/stem cell transplantation. This provides a new immune system to replace the one that ...

    Interview last updated 02/14/2017 - 8:34am.