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  1. Polymorphism of the complement receptor 1 gene correlates with hematological response to eculizumab in patients with paroxysmal nocturnal hemoglobinuria

    ... Primary Author:  Rondelli T Author(s):  Rondelli T, ... response is variable and some patients remain red blood cell transfusion -dependent. In 72 patients with hemolytic Paroxysmal ...

    Research Article last updated 09/26/2013 - 3:28pm.

  2. CASCADE (SGN33A-005)

    ... associated with favorable risk karyotypes including inv(16), t(8;21), t(16;16), or t(15;17) Patients who are candidates for allogeneic stem cell transplant at the time of enrollment Patients with a history of ...

    Clinical Trial last updated 06/19/2017 - 2:43pm.

  3. Successful treatment of aplastic anemia-paroxysmal nocturnal hemoglobinuria associated with eosinophilic fasciitis with matched unrelated donor allogeneic peripheral blood stem cell transplantation

    ... Sasaki K, Popat U, Jain P, Kadia T, Patel K, Patel K, Jain N, Takahashi K, Young K, Miranda RN, Oo TH, Lu H, ... aplastic anemia with allogeneic peripheral blood stem cell transplantation from a matched unrelated donor after multiple ...

    Research Article last updated 09/13/2016 - 12:49pm.

  4. The Effect of Decitabine Dose Modification and Myelosuppression on Response and Survival in Patients With Myelodysplastic Syndromes

    ... G, Cornelison AM, Cortes JE, Ravandi F, Daver N, Kadia T, Teng A, Kantarjian H Original Publication Date:  ... with MDS conducted Cox regression analyses of red blood cell or platelet dependence, myelosuppression, dose modification, ...

    Research Article last updated 06/02/2014 - 11:03am.

  5. Diagnostic screening of paroxysmal nocturnal hemoglobinuria: Prospective multicentric evaluation of the current medical indications

    ... Ángel Díaz J, Minguela A, Álvarez B, Serrano C, Caballero T, Rey M, Pérez Corral A, Cristina Fernández Jiménez M, Magro E, Lemes A, ... for patients presenting with thrombosis and normal blood cell counts. Bone Marrow Diseases:  ...

    Research Article last updated 10/06/2016 - 8:56am.

  6. A Rare Case of Aplastic Anemia Later in Life Doesn’t Stop Al Meyer

    ... I thought about selling my dealership, which I didn’t want to do -- but I still got my affairs in order.  However, I never gave in ... the start, I had been advised to start thinking about a stem cell transplantation. My brother was only a half match. But the NIH staff ...

    Patient Chronicle last updated 07/12/2017 - 1:52pm.

  7. Prospective assessment of effects on iron-overload parameters of deferasirox therapy in patients with myelodysplastic syndromes.

    ... Greenberg PL, Koller CA, Cabantchik ZI, Warsi G, Glynos T, Paley C, Schiffer C Original Publication Date:  ... 52 weeks of therapy despite ongoing receipt of red blood cell transfusions. Bone Marrow Diseases:  ...

    Research Article last updated 10/11/2011 - 5:58pm.

  8. Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation

    ... Background: - In allogeneic stem cell transplantation (SCT), stem cells are taken from a donor and given ... defined as complex karyotype (> 3 abnormalities); inv(3) or t(3;3); t(6;9); t(6;11); monosomy 7 ; trisomy 8, alone or with an ...

    Clinical Trial last updated 04/29/2016 - 1:00pm.

  9. Donor Atorvastatin Treatment in Preventing Severe Acute GVHD After Nonmyeloablative Peripheral Blood Stem Cell Transplant in Patients With Hematological Malignancies

    ... (GVHD) after nonmyeloablative peripheral blood stem cell (PBSC) transplant in patients with hematological malignancies. Giving low ... T 586 Other: Laboratory Biomarker Analysis Correlative studies Drug: ... Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation Undergo nonmyeloablative allogeneic PBSC ...

    Clinical Trial last updated 05/03/2016 - 9:44am.

  10. NHLBI profiles a member of the Foundation’s patient community.

    ... have no apparent origin. Emily first found out her blood cell counts were abnormally low when she was being treated for rheumatoid ... a weeklong, painful procedure, and unfortunately, it didn’t work,” Emily said. “My blood cell counts continued to drop.” Making ...

    Article last updated 06/13/2016 - 1:51pm.