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  1. Announcing AAMDSIF 2016 Research Awards

    ... set of clonal disorders characterized by ineffective blood cell development. These diseases are driven by many complex genetic and ... striking because we observed similar numbers of activated T lymphocytes and similar levels of pro-inflammatory cytokines, including ...

    Article last updated 06/09/2016 - 12:45pm.

  2. MDS - Treatment (OLD)

    ... May or may not need blood transfusions, depending on blood cell counts Have a low or intermediate-1 risk IPSS score, which is between ... bone marrow to make more red blood cells. If you don't have enough natural EPO or if you have anemia, your doctor may prescribe a ...

    Topic section last updated 03/10/2016 - 11:01pm.

  3. T-cell Depleted Alternative Donor Transplantation

    ... is to determine the ability of CD34+ selection and T cell depletion using the CliniMACS® device to prevent severe acute ...

    Clinical Trial last updated 04/29/2016 - 3:38pm.

  4. Types of Blood Transfusions

    ... failure disease patients are: Red blood cell transfusion Platelet transfusion More on ... cells in the blood that help stop bleeding. People who don’t have enough platelets have a high risk of dangerous bleeding. Each whole ...

    Page last updated 10/31/2014 - 2:34pm.

  5. Types

    ... < 5 5 - 20 RAEB-t (Refractory Anemia with Excess Blasts in Transformation) > ... Considered the mildest category. MDS is limited to one cell line. There is little dysplasia. Has 3 subtypes: ...

    Topic section last updated 11/14/2016 - 1:11pm.

  6. Iron Chelation

    ... blood cells contain iron. Each time you get a red blood cell transfusion you are putting more iron in your body. Your body has no ... accumulate in these 3 organs and in other organs that don't normally store iron, such as the pancreas, heart, joints and skin. This ...

    Topic section last updated 06/23/2016 - 3:56pm.

  7. Predicting response to immunosuppressive therapy in childhood aplastic anemia.

    ... Hama A, Takahashi Y, Kosaka Y, Kobayashi R, Yabe H, Kaneko T, Tsuchida M, Ohara A, Nakahata T, Kojima S. Original ... . In multivariate analyses, lower white blood cell count was the most significant predictive marker of better response; ...

    Research Article last updated 10/11/2011 - 5:58pm.

  8. AAMDSIF Summer Fellowship Grant Program

    ... aplastic anemia ,’ investigating how CD4 and CD8 T cells interact to influence bone marrow failure . She described ... failure are largely unknown. T cells, one type of immune cell, have long been known to be expanded in the bone marrow of aplastic anemia ...

    Page last updated 05/17/2017 - 1:29pm.

  9. Finding a Stem Cell Donor

    ... you may be a candidate for a bone marrow / stem cell transplant in the future, start looking for a donor right away. Only ... 7 out of 10 of patients who need a transplant don't find a matching donor in their family. If you need an unrelated donor, your ...

    Page last updated 05/14/2015 - 9:46am.

  10. Polymorphism of the complement receptor 1 gene correlates with hematological response to eculizumab in patients with paroxysmal nocturnal hemoglobinuria

    ... Primary Author:  Rondelli T Author(s):  Rondelli T, ... response is variable and some patients remain red blood cell transfusion -dependent. In 72 patients with hemolytic Paroxysmal ...

    Research Article last updated 09/26/2013 - 3:28pm.