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  1. Palifermin With Leuprolide Acetate for the Promotion of Immune Recovery Following Total Body Irradiation Based T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation

    ... help the immune system recover faster following a stem cell transplant . Blood stem cells are very young blood cells that ... AML does not have "good risk" cytogenetic features (i.e. t (8;21), t(15;17), inv 16 without c-kit mutations). Secondary AML in ...

    Clinical Trial last updated 04/29/2016 - 1:11pm.

  2. A Rare Case of Aplastic Anemia Later in Life Doesn’t Stop Al Meyer

    ... I thought about selling my dealership, which I didn’t want to do -- but I still got my affairs in order.  However, I never gave in ... the start, I had been advised to start thinking about a stem cell transplantation. My brother was only a half match. But the NIH staff ...

    Patient Chronicle last updated 07/12/2017 - 1:52pm.

  3. CASCADE (SGN33A-005)

    ... associated with favorable risk karyotypes including inv(16), t(8;21), t(16;16), or t(15;17) Patients who are candidates for allogeneic stem cell transplant at the time of enrollment Patients with a history of ...

    Clinical Trial last updated 06/19/2017 - 2:43pm.

  4. Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    ... This pilot phase II trial studies how well giving donor T cells after donor stem cell transplant works in treating patients with hematologic malignancies. ...

    Clinical Trial last updated 05/03/2016 - 11:17am.

  5. Symptoms

    ... but it does not darken in all cases Low red blood cell count ( anemia ) which can cause you to: Feel tired Have ... seek immediate medical help if they have bleeding that can’t be stopped by usual methods, such as applying pressure to the area. ...

    Topic section last updated 03/29/2016 - 6:18pm.

  6. Identification of novel microRNA signatures linked to acquired aplastic anemia

    ... investigated in acquired aplastic anemia , a T cell -mediated immune disease. Analysis of 84 miRNA expression levels in ...

    Research Article last updated 10/12/2015 - 10:00am.

  7. Types

    ... < 5 5 - 20 RAEB-t (Refractory Anemia with Excess Blasts in Transformation) > ... Considered the mildest category. MDS is limited to one cell line. There is little dysplasia. Has 3 subtypes: ...

    Topic section last updated 11/14/2016 - 1:11pm.

  8. Personalized Natural Killer (NK) Cell Therapy in Cord Blood Transplantation (CBT)

    ... -7/7q-, abn(12p), abn(17p), MLL gene re-arrangement and t (6;9)47, flt3 mutation positive and/or evidence of minimal residual ... (including relapse post autologous hematopoietic stem cell transplant ). Relapsed double hit lymphomas. Patients with options for ...

    Clinical Trial last updated 06/06/2016 - 10:28am.

  9. Announcing AAMDSIF 2016 Research Awards

    ... set of clonal disorders characterized by ineffective blood cell development. These diseases are driven by many complex genetic and ... striking because we observed similar numbers of activated T lymphocytes and similar levels of pro-inflammatory cytokines, including ...

    Article last updated 06/09/2016 - 12:45pm.

  10. Iron Chelation

    ... blood cells contain iron. Each time you get a red blood cell transfusion you are putting more iron in your body. Your body has no ... accumulate in these 3 organs and in other organs that don't normally store iron, such as the pancreas, heart, joints and skin. This ...

    Topic section last updated 06/23/2016 - 3:56pm.