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  1. Treosulfan and Fludarabine Phosphate With or Without Total Body Irradiation Before Donor Stem Cell Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia

    ... with or without total body irradiation before donor stem cell transplant works in treating patients with myelodysplastic syndrome ... phosphate, and total-body irradiation before a donor stem cell transplant helps stop the growth of cancer cells. It may also stop the ... T 586 Other: Laboratory Biomarker Analysis Correlative studies Procedure: ...

    Clinical Trial last updated 04/28/2016 - 1:05pm.

  2. Memory Stem T Cells in Autoimmune Disease: High Frequency of Circulating CD8+ Memory Stem Cells in Acquired Aplastic Anemia

    ... Memory stem T cells (TSCMs) constitute a long-lived, self-renewing lymphocyte ... pathogenesis are abnormal CD4(+) and CD8(+) T cell activation. We investigated the TSCM subset in 55, 34, 43, and 5 ...

    Research Article last updated 04/29/2016 - 12:59pm.

  3. Reduced-Intensity Conditioning Before Donor Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignancies

    ... studies reduced-intensity conditioning before donor stem cell transplant in treating patients with high-risk hematologic ... and total-body irradiation before a donor stem cell transplant helps stop the growth of cancer cells. It may also stop the ... effect). Giving an infusion of the donor's T cells (donor lymphocyte infusion) after the transplant may help ...

    Clinical Trial last updated 05/03/2016 - 10:51am.

  4. Approved: New blood cancer detection tool

    ... illuminated by the T1 and T2 reagents are found on a T and natural killer (NK) cell populations. These reagents can be used along with clinical parameters for ...

    Article last updated 07/05/2017 - 10:30am.

  5. Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    ... phase II trial studies how well donor peripheral blood stem cell (PBSC) transplant works in treating patients with hematologic ... a matched, unrelated donor Acute leukemias (includes T lymphoblastic lymphoma); remission is defined as < 5% blasts with no ...

    Clinical Trial last updated 04/29/2016 - 3:26pm.

  6. Thankful to Be Here and Alive

    ... was used to being sick and fighting through it, so I didn’t think much about it. I started antibiotics while I continued going to school ... out of my doctor’s mouth: cancer. He thought with my white cell count so low that leukemia was a possibility. He called several hospitals ...

    Patient Chronicle last updated 04/26/2018 - 10:42am.

  7. Acute leukaemia and myelodysplastic syndromes with chromosomal rearrangement involving 11q23 locus, but not MLL gene

    ... AML, two with B-lymphoblastic leukaemia (B-ALL); two with T-lymphoblastic leukaemia (T-ALL), two with myelodysplastic syndrome (MDS) and ... patients received risk-adapted therapies, including stem cell transplant in five patients. At the last follow-up, eight patients ...

    Research Article last updated 09/19/2016 - 11:12am.

  8. Identification of novel microRNA signatures linked to acquired aplastic anemia

    ... investigated in acquired aplastic anemia , a T cell -mediated immune disease. Analysis of 84 miRNA expression levels in ...

    Research Article last updated 10/12/2015 - 10:00am.

  9. Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    ... population defined as: patients with hematopoietic cell transplant (HCT)-co-morbidity index (CI)/age scores >= 2, but no more than ... Total-Body Irradiation Undergo TBI Biological: T Cell-Depleted Donor Lymphocyte Infusion Undergo DLI Drug: ...

    Clinical Trial last updated 04/27/2016 - 1:37pm.

  10. Shares her 11-year-old daughter's story

    ... a transplant team but that option scared us and we weren’t quite ready to go with a matched unrelated donor . One was found, but ... for nearly a year. With lower white blood cell counts there are still challenges with potential infections, she still ...

    Patient Chronicle last updated 01/04/2017 - 11:09am.