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  1. Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    ... population defined as: patients with hematopoietic cell transplant (HCT)-co-morbidity index (CI)/age scores >= 2, but no more than ... Total-Body Irradiation Undergo TBI Biological: T Cell-Depleted Donor Lymphocyte Infusion Undergo DLI Drug: ...

    Clinical Trial last updated 04/27/2016 - 1:37pm.

  2. Aplastic Anemia and MDS International Foundation (AAMDSIF): Bone marrow failure disease scientific symposium 2016

    ... Zeidan AM, Battiwalla M, Berlyne D, Winkler T Original Publication Date:  ... due to impairments of the hematopoietic stem cell compartment. Common manifestations of BMFS include varying degrees of ...

    Research Article last updated 01/24/2017 - 11:54am.

  3. Palifermin With Leuprolide Acetate for the Promotion of Immune Recovery Following Total Body Irradiation Based T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation

    ... help the immune system recover faster following a stem cell transplant . Blood stem cells are very young blood cells that ... AML does not have "good risk" cytogenetic features (i.e. t (8;21), t(15;17), inv 16 without c-kit mutations). Secondary AML in ...

    Clinical Trial last updated 04/29/2016 - 1:11pm.

  4. Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    ... This pilot phase II trial studies how well giving donor T cells after donor stem cell transplant works in treating patients with hematologic malignancies. ...

    Clinical Trial last updated 05/03/2016 - 11:17am.

  5. Identification of novel microRNA signatures linked to acquired aplastic anemia

    ... investigated in acquired aplastic anemia , a T cell -mediated immune disease. Analysis of 84 miRNA expression levels in ...

    Research Article last updated 10/12/2015 - 10:00am.

  6. Symptoms

    ... but it does not darken in all cases Low red blood cell count ( anemia ) which can cause you to: Feel tired Have ... seek immediate medical help if they have bleeding that can’t be stopped by usual methods, such as applying pressure to the area. ...

    Topic section last updated 03/29/2016 - 6:18pm.

  7. MDS Follows Two Misdiagnoses

    ... me and my last azacitidine (Vidaza®) treatment in June didn't seem to have much benefit. I live in Colorado at 8600 feet elevation, and ... I was walking because my hemoglobin was 3.00 and my white cell count was 1.00. I spent a week in the hospital, got 7 units of blood ...

    Patient Chronicle last updated 12/27/2016 - 7:23am.

  8. The diagnosis and treatment of aplastic anemia: a review

    ... pancytopenia . A trigger-related abnormal T cell response facilitated by some genetic predisposition has been ... is not available for transplant. MSD hematopoietic stem cell transplantation (HSCT) is associated with cure in ~90 % of patients. ...

    Research Article last updated 05/26/2015 - 10:30am.

  9. Personalized Natural Killer (NK) Cell Therapy in Cord Blood Transplantation (CBT)

    ... -7/7q-, abn(12p), abn(17p), MLL gene re-arrangement and t (6;9)47, flt3 mutation positive and/or evidence of minimal residual ... (including relapse post autologous hematopoietic stem cell transplant ). Relapsed double hit lymphomas. Patients with options for ...

    Clinical Trial last updated 06/06/2016 - 10:28am.

  10. Oral Azacitidine (CC-486) for the Treatment of Myelodysplastic Syndromes and Acute Myeloid Leukemia

    ... Author(s):  Cogle CR, Scott BL, Boyd T, Garcia-Manero G Original Publication Date:  ... therapy for patients with AML not eligible for stem cell transplant , and as maintenance therapy for patients with MDS or AML ...

    Research Article last updated 12/09/2015 - 8:49am.