Search | Page 3 | Aplastic Anemia and MDS International Foundation

Search

Search results

  1. Laboratory tests for paroxysmal nocturnal hemoglobinuria (PNH).

    ... mutations in the Phosphatidylinositol Glycan class A (PIG-A) gene in the hematopoietic stem cells (HSC) of patients. The presence of ...

    Research Article last updated 10/22/2013 - 3:44pm.

  2. Clinical roundtable monograph: Paroxysmal nocturnal hemoglobinuria: a case-based discussion.

    ... by the acquisition of a somatic mutation of the gene phosphatidylinositol glycan anchor (PIG-A) in a multipotent hematopoietic stem cell (HSC), with clonal expansion of ...

    Research Article last updated 05/14/2013 - 3:28pm.

  3. Paroxysmal nocturnal hemoglobinuria and the complement system: recent insights and novel anticomplement strategies

    ... in the X-linked phosphatidylinositol glycan class A (PIG-A) gene, which impairs the membrane expression on affected blood cells of a number ...

    Research Article last updated 03/05/2013 - 9:38am.

  4. Paroxysmal nocturnal hemoglobinuria and the complement system: recent insights and novel anticomplement strategies

    ... in the X-linked phosphatidylinositol glycan class A (PIG-A) gene, which impairs the membrane expression on affected blood cells of a number ...

    Research Article last updated 10/02/2012 - 9:57am.

  5. Guidelines for the diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria and related disorders by flow cytometry.

    ... characterized by a somatic mutation in the PIGA gene, leading to a deficiency of proteins linked to the cell membrane via ...

    Research Article last updated 10/11/2011 - 5:58pm.

  6. PNH - Basics

    ... the cells from being attacked by the complement system. The gene in charge of making this protective shield is called PIG-A. ...

    Topic section last updated 04/05/2016 - 4:02pm.

  7. AA&MDSIF announces PNH grant awards

    ... . PNH is caused by a somatic mutation in the PIG-A gene , which is responsible for a cellular protein deficiency that is ...

    Article last updated 12/14/2016 - 11:41am.

  8. Interviews with the Experts: Hemolysis in PNH and Beyond

    ... happens in PNH is that an acquired mutation in a gene ( PIG-A gene ) in hematopoietic stem cells results in their inability ...

    Interview last updated 08/31/2016 - 8:40am.

  9. Clone of Patients

    ...

    Page last updated 03/14/2016 - 6:05pm.

  10. Causes

    ... because of a change ( mutation ) in the PIG-A gene of a single stem cell in your bone marrow . This gene controls ...

    Topic section last updated 03/29/2016 - 6:15pm.