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  1. Clinical activity and safety of the dual pathway inhibitor rigosertib for higher risk myelodysplastic syndromes following DNA methyltransferase inhibitor therapy

    ... (88%) had higher risk disease according to the Revised International Prognostic Scoring System . Median overall survival for this group of 39 ...

    Research Article last updated 05/22/2014 - 10:23am.

  2. p53 protein expression independently predicts outcome in patients with lower-risk myelodysplastic syndromes with del(5q)

    ... International Prognostic Scoring System -defined Low- or Intermediate-1-risk (lower-risk) ...

    Research Article last updated 04/23/2014 - 12:26pm.

  3. Myelodysplastic syndromes

    ... of MDS, risk evaluation according to established prognostic assessment tools (including the new revised International Prognostic Scoring System ), treatment options according to ...

    Research Article last updated 08/06/2013 - 12:31pm.

  4. Comparison of risk stratification tools in predicting outcomes of patients with higher-risk myelodysplastic syndromes treated with azanucleosides

    ... Established prognostic tools in patients with myelodysplastic syndromes (MDS) were ... database, we compared the prognostic utility of the International Prognostic Scoring System (IPSS), revised IPSS (IPSS-R), MD ...

    Research Article last updated 12/09/2015 - 8:46am.

  5. Methylation of the p73 gene in patients with myelodysplastic syndromes: correlations with apoptosis and prognosis

    ... of p73 methylation was significantly correlated with the International Prognostic Scoring System subgroup ( r  =  0.904, p  <  0.001). ...

    Research Article last updated 11/05/2012 - 10:10am.

  6. Combination strategies in myelodysplastic syndromes.

    ... as higher risk and lower risk on the basis of the International Prognostic Scoring System . Currently, lenalidomide , azacitidine ...

    Research Article last updated 04/24/2012 - 2:18pm.

  7. Perceptions of Disease State, Treatment Outcomes, and Prognosis Among Patients with Myelodysplastic Syndromes: Results From an Internet-Based Survey.

    ... was 6 years. Many patients (55%) did not know their International Prognostic Scoring System score, 42% were unaware of their blast ...

    Research Article last updated 10/11/2011 - 5:58pm.

  8. Continued azacitidine therapy beyond time of first response improves quality of response in patients with higher-risk myelodysplastic syndromes.

    ... with conventional care regimens in patients with International Prognostic Scoring System -defined intermediate-2- or high-risk myelodysplastic ...

    Research Article last updated 10/11/2011 - 5:58pm.

  9. Azacitidine for treatment of patients with myelodysplastic syndromes (MDS): practical recommendations of the German MDS Study Group.

    ... to conventional care regimens for patients with International Prognostic Scoring System score of intermediate-2 or high-risk MDS. This review aims ...

    Research Article last updated 10/11/2011 - 5:58pm.

  10. Durable long-term responses in patients with myelodysplastic syndromes treated with lenalidomide.

    ... yet been reported. Here, we describe 6 patients with International Prognostic Scoring System low- or intermediate-1-risk MDS who began ...

    Research Article last updated 10/11/2011 - 5:58pm.