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  1. Impact of tobacco usage on disease outcome in myelodysplastic syndromes

    ... We hypothesized that tobacco usage is an independent prognostic factor in patients with myelodysplastic syndromes (MDS). To ... intermediate-1 (int-1) risk at diagnosis based on the International Prognostic Scoring System for MDS. In patients with ...

    Research Article last updated 06/03/2015 - 1:34pm.

  2. Bone marrow fibrosis in patients with primary myelodysplastic syndromes has prognostic value using current therapies and new risk stratification systems.

    ... syndromes . In this study, we assessed the prognostic impact of bone marrow fibrosis in patients with primary ... stratification systems: the New Comprehensive Cytogenetic Scoring System and the Revised International Prognostic Scoring System . From 2002 to 2012, a total of 79 ...

    Research Article last updated 11/14/2013 - 11:30am.

  3. Comparison of risk stratification tools in predicting outcomes of patients with higher-risk myelodysplastic syndromes treated with azanucleosides

    ... 2015 Established prognostic tools in patients with myelodysplastic syndromes (MDS) were ... database, we compared the prognostic utility of the International Prognostic Scoring System (IPSS), revised IPSS (IPSS-R), MD ...

    Research Article last updated 12/09/2015 - 8:46am.

  4. High levels of vascular endothelial growth factor protein expression are associated with an increased risk of transfusion dependence in myelodysplastic syndromes

    ... We evaluated the prognostic significance of vascular endothelial growth factor (VEGF) ... and overall survival. The inclusion of VEGFi in the International Prognostic Scoring System and WPSS maintained its significant ...

    Research Article last updated 03/05/2013 - 9:11am.

  5. Prognostic value of self-reported fatigue on overall survival in patients with myelodysplastic syndromes: a multicentre, prospective, observational, cohort study

    ... severity predicts overall survival beyond gold-standard prognostic indices in patients with higher-risk myelodysplastic syndromes. ... intermediate-2-risk or high-risk score according to the International Prognostic Scoring System (IPSS). Patients were enrolled ...

    Research Article last updated 11/10/2015 - 10:47am.

  6. Development and validation of a model to predict platelet response to romiplostim in patients with lower-risk myelodysplastic syndromes

    ... trial of 250 thrombocytopenic, lower-risk MDS patients ( International Prognostic Scoring System low/intermediate-1). A predictive scoring system ...

    Research Article last updated 08/04/2014 - 8:33am.

  7. Tea consumption reduces the risk of de novo myelodysplastic syndromes

    ... and 'intermediated/poor' prognosis groups, and in the International Prognostic Scoring System lower and higher risk groups, but not in the ...

    Research Article last updated 01/20/2015 - 12:56pm.

  8. Phase II clinical study of erlotinib for treatment of myelodysplastic syndromes

    ... failure. All intermediate-2 or high-risk MDS patients by International Prognostic Scoring System and only those low/intermediate-1 patients with ...

    Research Article last updated 05/22/2014 - 10:33am.

  9. Clinical activity and safety of the dual pathway inhibitor rigosertib for higher risk myelodysplastic syndromes following DNA methyltransferase inhibitor therapy

    ... (88%) had higher risk disease according to the Revised International Prognostic Scoring System . Median overall survival for this group of 39 ...

    Research Article last updated 05/22/2014 - 10:23am.

  10. Myelodysplastic syndromes: 2011 update on diagnosis, risk-stratification, and management

    ... characteristics. The most commonly used system is the International Prognostic Scoring System . This score divides patients into a lower risk ...

    Research Article last updated 10/11/2011 - 5:58pm.