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  1. Targeted next-generation sequencing in myelodysplastic syndromes and prognostic interaction between mutations and IPSS-R

    ... (MDS); risk distribution according to the revised International Prognostic Scoring System (IPSS-R) was 11% very high, 18% high, 17% ...

    Research Article last updated 09/18/2017 - 11:05am.

  2. Luspatercept for the treatment of anaemia in patients with lower-risk myelodysplastic syndromes (PACE-MDS): a multicentre, open-label phase 2 dose-finding study with long-term extension study

    ... eligible patients were aged 18 years or older, had International Prognostic Scoring System -defined low or intermediate 1 risk ...

    Research Article last updated 09/18/2017 - 1:38pm.

  3. First-line Therapeutic Strategies for Myelodysplastic Syndromes.

    ... The precise diagnostic tests and subsequent prognostic stratification for patients with myelodysplastic syndrome (MDS) are ... not grounded on the available evidence. Although the International Prognostic Scoring System and revised International ...

    Research Article last updated 09/11/2017 - 8:44am.

  4. New Insight Into the Biology, Risk Stratification, and Targeted Treatment of Myelodysplastic Syndromes

    ... of mutated genes within a class. In addition to the prognostic significance of individual somatic mutations, more somatic mutations ... for risk stratification are available with the revised International Prognostic Scoring System (IPSS-R), currently considered the ...

    Research Article last updated 06/26/2017 - 9:16am.

  5. Prognostic relevance of lymphocytopenia, monocytopenia and lymphocyte-to-monocyte ratio in primary myelodysplastic syndromes: a single center experience in 889 patients

    ... 31, 2017 Current prognostic models for myelodysplastic syndromes (MDS), including the Revised International Prognostic Scoring System (IPSS-R), do not account for host ...

    Research Article last updated 05/02/2017 - 10:37am.

  6. Incorporation of molecular data into the Revised International Prognostic Scoring System in treated patients with myelodysplastic syndromes

    ... The Revised International Prognostic Scoring System (IPSS-R) was developed for untreated ...

    Research Article last updated 11/28/2016 - 9:42am.

  7. Infectious complications in patients with myelodysplastic syndromes: a review of the literature with emphasis on patients treated with 5-azacitidine

    ... particular subtypes within the FAB classification1 . The international prognostic scoring system (IPSS) was the first to include - beside ...

    Research Article last updated 04/14/2017 - 10:41am.

  8. Comparison of clinical outcomes and prognostic utility of risk stratification tools in patients with therapy-related vs de novo myelodysplastic syndromes: a report on behalf of the MDS Clinical Research Consortium.

    ... some t-MDS patients have an indolent course. Most MDS prognostic models excluded t-MDS patients during development. The performances of the International Prognostic Scoring System (IPSS), revised IPSS (IPSS-R), MD ...

    Research Article last updated 03/09/2017 - 1:27pm.

  9. Outcome of Lower-Risk Patients With Myelodysplastic Syndromes Without 5q Deletion After Failure of Erythropoiesis-Stimulating Agents

    ... second-line treatments. Patients and Methods We examined an international retrospective cohort of 1,698 patients with non-del(5q) ... analysis adjusted for age, sex, revised International Prognostic Scoring System score, and progression at ESA failure, there was ...

    Research Article last updated 04/14/2017 - 9:09am.

  10. Outcomes after Umbilical Cord Blood Transplantation for Myelodysplastic Syndromes

    ... MDS patients underwent UCBT as reported to the Center for International Blood and Marrow Transplant Research. Median age at the time of ... 19% high, and 13% very high-risk Revised International Prognostic Scoring System (IPSS-R) scores, respectively. The 100-day ...

    Research Article last updated 03/22/2017 - 9:24am.