Search | Page 10 | Aplastic Anemia and MDS International Foundation

Search

Search results

  1. Reduced Intensity Conditioning in Patients Aged ≤35 With Non-Malignant Disorders Undergoing UCBT, BMT, or PBSCT (RIC HSCT NMD)

    ... all diagnoses. Patients must have a 4/6, 5/6 or 6/6 HLA matched related or unrelated UCB unit available that will deliver a ... 2x10e7 cells/kg. Patients must have an 8 of 8 or 7 of 8 HLA allele level matched unrelated donor bone marrow or ...

    Clinical Trial last updated 06/13/2016 - 2:18pm.

  2. Safety and Efficacy of Two Doses of ATIR101, a T-lymphocyte Enriched Leukocyte Preparation Depleted of Host Alloreactive T-cells, in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donor

    ... family donor with 2 to 3 mismatches at the HLA -A, -B and/or -DR loci of the unshared haplotype Male or female, age ... ATIR101 (e.g., dimethyl sulfoxide) Known presence of HLA antibodies against the non-shared donor haplotype Any other ...

    Clinical Trial last updated 04/29/2016 - 12:25pm.

  3. Non-Myeloablative Conditioning for Unrelated Donor Umbilical Cord Blood Transplant

    ... Age, Graft Cell Dose and Graft HLA Criteria Subjects must be <70 years old. Subjects ages ≥ 70 and ... (HCT-CI) score ≤ 2. The UCB graft is matched at 4-6 HLA-A, B, DRB1 antigens with the recipient. Patients co-enrolled in ...

    Clinical Trial last updated 05/02/2016 - 2:13pm.

  4. Hematopoietic Stem Cell Transplantation in Aplastic Anemia

    ... best candidates.   For young patients lacking an HLA -matched sibling donor, immunosuppressive therapy (IST) with ... deciding between IST versus transplant is how quickly an HLA-matched donor can be found and cleared for collection. Donor availability ...

    Interview last updated 11/28/2016 - 2:58pm.

  5. Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

    ... undergo allogeneic stem cell transplantation from an HLA identical sibling or match unrelated donor using the identical ... inclusive), and weight > 18kg     Availability of HLA identical or single HLA locus mismatched family donor or 10/10 matched ...

    Clinical Trial last updated 04/28/2016 - 2:40pm.

  6. Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    ... Molecular based human leukocyte antigen ( HLA ) typing will be performed for the HLA-A, -B, -Cw, -DRB1 and -DQB1 loci to the resolution adequate to establish ...

    Clinical Trial last updated 04/29/2016 - 3:26pm.

  7. Fludarabine Phosphate and Total Body Irradiation Followed by a Donor Peripheral Stem Cell Transplant in Treating Patients With Myelodysplastic Syndromes or Myeloproliferative Disorders

    ... failed HCT An human leukocyte antigen ( HLA )-identical related or an HLA-matched unrelated donor (Fred Hutchinson Cancer Research Center ...

    Clinical Trial last updated 04/28/2016 - 2:45pm.

  8. StemRegenin-1 Expanded vs Unexpanded UCB for High Risk Heme Malignancies

    ... Must have a partially HLA matched UCB unit with a pre-cryopreserved TNC dose >2.5 x 107 per kilogram recipient weight. HLA matching is initially based on 4 of 6 HLA-A and B (at low or intermediate resolution by molecular typing) and DRB1 ...

    Clinical Trial last updated 06/03/2016 - 2:37pm.

  9. Azacitidine in Haploidentical Donor Hematopoietic Cell Transplantation

    ... (ALL); however, human leukocyte antigen ( HLA )-matched donor availability continues to be a major hurdle. Historically, HLA haploidentical donor hematopoietic cell transplantation (haplo-HCT) was ...

    Clinical Trial last updated 05/03/2016 - 11:15am.

  10. Cord Blood Transplant

    ... peripheral blood from a Human Leukocyte Antigen ( HLA ) matched sibling donor is the most commonly used source of allogeneic stem cells . However, HLA matched siblings are available for less than one third of the patients who ...

    Clinical Trial last updated 04/27/2016 - 9:59am.