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  1. Reduced intensity conditioning, combined transplantation of haploidentical hematopoietic stem cells and mesenchymal stem cells in patients with severe aplastic anemia

    ... of haploidentical HSCs and MSCs on SAA without an HLA -identical sibling donor was safe, effectively reduced the incidence of ...

    Research Article last updated 04/09/2014 - 9:16am.

  2. Optimization of therapy for severe aplastic anemia based on clinical, biologic, and treatment response parameters: conclusions of an international working group on severe aplastic anemia convened by the Blood and Marrow Transplant Clinical Trials Network.

    ... donor transplantation approaches for patients lacking HLA -matched unrelated donors must be improved. A partnership of BMT, IST, ...

    Research Article last updated 10/11/2011 - 5:58pm.

  3. RIC Transplant Using Haplo Donors

    ... of a reduced intensity allogeneic HSCT from partially HLA -mismatched first-degree relatives utilizing PBSC as the stem cell ... transplant Availability of 3/6 - 5/6 matched ( HLA -A, B, DR) related donor (donor must have negative HLA cross-match in ...

    Clinical Trial last updated 04/29/2016 - 10:52am.

  4. Finding a Stem Cell Donor

    ... sample to test for your human leukocyte antigen ( HLA ) type. HLA are proteins found on most cells in your body. Your immune system uses ...

    Page last updated 05/14/2015 - 9:46am.

  5. Inducible Regulatory T Cells (iTregs) in Non-Myeloablative Sibling Donor Peripheral Blood Stem Cell Transplantation

    ... given to adult patients undergoing non-myeloablative HLA -identical sibling donor peripheral blood stem cell (PBSC) ... 18 - 75 years of age with an HLA -identical sibling donor One of the following disease categories: ...

    Clinical Trial last updated 04/29/2016 - 1:48pm.

  6. Combined Bone Marrow and Renal Transplantation for Hematologic Disorders With End Stage Renal Disease

    ... and assess complication rates for genetically ( HLA ) matched related donor combined ... 18 - 65 years of age. Participants must have an HLA -matched or one of six HLA A, B, or DR antigen-mismatched related donor, ...

    Clinical Trial last updated 06/06/2016 - 3:04pm.

  7. Safety and Efficacy of BL-8040 for the Mobilization of Donor Hematopoietic

    ... based on the following hypotheses: Healthy HLA -matched donors receiving one injection of BL-8040 will mobilize ... engraftment following transplantation into HLA-identical siblings with advanced hematological malignancies using various ... status of 0 or 1. PART 1: Donor must be a 5/6 or 6/6 HLA -matched sibling willing to donate PBSC for transplant. PART 2: ...

    Clinical Trial last updated 04/29/2016 - 4:33pm.

  8. Bone Marrow and Stem Cell Transplantation

    ... sample to test for your human leukocyte antigen ( HLA ) type. HLA are proteins found on most cells in your body. Your immune system uses ...

    Page last updated 09/30/2014 - 11:47am.

  9. Nonmyeloablative Haploidentical Transplant Followed by MLN9708

    ... well documented effect of NK cell alloreactivity seen in HLA -mismatched transplantation. These strategies include (1) choosing ... Availability of a 3/6 - 5/6 matched ( HLA -A, B, DR) related donor Donor must have negative HLA cross-match in ...

    Clinical Trial last updated 04/29/2016 - 1:05pm.

  10. Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation

    ... and donor have similar human leukocyte antigens ( HLA ). Researchers want to see if the drug palifermin improves the results of allogeneic SCT from HLA-matched unrelated donors. Objective: - To see if high doses of ...

    Clinical Trial last updated 04/29/2016 - 1:00pm.