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  1. RIC Transplant Using Haplo Donors

    ... of a reduced intensity allogeneic HSCT from partially HLA -mismatched first-degree relatives utilizing PBSC as the stem cell ... transplant Availability of 3/6 - 5/6 matched ( HLA -A, B, DR) related donor (donor must have negative HLA cross-match in ...

    Clinical Trial last updated 04/29/2016 - 10:52am.

  2. Finding a Stem Cell Donor

    ... sample to test for your human leukocyte antigen ( HLA ) type. HLA are proteins found on most cells in your body. Your immune system uses ...

    Page last updated 05/14/2015 - 9:46am.

  3. Combined Bone Marrow and Renal Transplantation for Hematologic Disorders With End Stage Renal Disease

    ... and assess complication rates for genetically ( HLA ) matched related donor combined ... 18 - 65 years of age. Participants must have an HLA -matched or one of six HLA A, B, or DR antigen-mismatched related donor, ...

    Clinical Trial last updated 06/06/2016 - 3:04pm.

  4. Inducible Regulatory T Cells (iTregs) in Non-Myeloablative Sibling Donor Peripheral Blood Stem Cell Transplantation

    ... given to adult patients undergoing non-myeloablative HLA -identical sibling donor peripheral blood stem cell (PBSC) ... 18 - 75 years of age with an HLA -identical sibling donor One of the following disease categories: ...

    Clinical Trial last updated 04/29/2016 - 1:48pm.

  5. Safety and Efficacy of BL-8040 for the Mobilization of Donor Hematopoietic

    ... based on the following hypotheses: Healthy HLA -matched donors receiving one injection of BL-8040 will mobilize ... engraftment following transplantation into HLA-identical siblings with advanced hematological malignancies using various ... status of 0 or 1. PART 1: Donor must be a 5/6 or 6/6 HLA -matched sibling willing to donate PBSC for transplant. PART 2: ...

    Clinical Trial last updated 04/29/2016 - 4:33pm.

  6. Nonmyeloablative Haploidentical Transplant Followed by MLN9708

    ... well documented effect of NK cell alloreactivity seen in HLA -mismatched transplantation. These strategies include (1) choosing ... Availability of a 3/6 - 5/6 matched ( HLA -A, B, DR) related donor Donor must have negative HLA cross-match in ...

    Clinical Trial last updated 04/29/2016 - 1:05pm.

  7. Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation

    ... and donor have similar human leukocyte antigens ( HLA ). Researchers want to see if the drug palifermin improves the results of allogeneic SCT from HLA-matched unrelated donors. Objective: - To see if high doses of ...

    Clinical Trial last updated 04/29/2016 - 1:00pm.

  8. Bone Marrow and Stem Cell Transplantation

    ... sample to test for your human leukocyte antigen ( HLA ) type. HLA are proteins found on most cells in your body. Your immune system uses ...

    Page last updated 09/30/2014 - 11:47am.

  9. Reduced Intensity Conditioning in Patients Aged ≤35 With Non-Malignant Disorders Undergoing UCBT, BMT, or PBSCT (RIC HSCT NMD)

    ... all diagnoses. Patients must have a 4/6, 5/6 or 6/6 HLA matched related or unrelated UCB unit available that will deliver a ... 2x10e7 cells/kg. Patients must have an 8 of 8 or 7 of 8 HLA allele level matched unrelated donor bone marrow or ...

    Clinical Trial last updated 06/13/2016 - 2:18pm.

  10. Safety and Efficacy of Two Doses of ATIR101, a T-lymphocyte Enriched Leukocyte Preparation Depleted of Host Alloreactive T-cells, in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donor

    ... family donor with 2 to 3 mismatches at the HLA -A, -B and/or -DR loci of the unshared haplotype Male or female, age ... ATIR101 (e.g., dimethyl sulfoxide) Known presence of HLA antibodies against the non-shared donor haplotype Any other ...

    Clinical Trial last updated 04/29/2016 - 12:25pm.