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  1. Aplastic anemia: first-line treatment by immunosuppression and sibling marrow transplantation.

    ... A for patients without a sibling donor and HLA identical sibling transplant for patients younger than age 40 with a ...

    Research Article last updated 10/11/2011 - 5:58pm.

  2. Aplastic anemia: pathophysiology and treatment.

    ... transplantation (HSCT) for acquired AA, whether from an HLA identical sibling or an unrelated donor , provides an excellent ...

    Research Article last updated 10/11/2011 - 5:58pm.

  3. Value of allogeneic versus autologous stem cell transplantation and chemotherapy in patients with myelodysplastic syndromes and secondary acute myeloid leukemia. Final results of a prospective randomized European Intergroup Trial.

    ... chemotherapy, the impact of the availability of an HLA -identical sibling donor on an intention-to treat basis. Additionally, ...

    Research Article last updated 10/11/2011 - 5:58pm.

  4. Transplantation strategies for the management of patients with myelodysplastic syndromes.

    ... mortality (TRM) and availability of a suitable HLA -matched donor. Results from several large centres indicated 3-year ...

    Research Article last updated 10/11/2011 - 5:58pm.

  5. Emergence of clonal hematopoiesis in the majority of patients with acquired aplastic anemia

    ... syndrome. Two patients had oligoclonal loss of the HLA alleles, linking immune escape to clone emergence. Two ...

    Research Article last updated 04/07/2015 - 1:05pm.

  6. Role of Reduced-Intensity Conditioning Allogeneic Hematopoietic Stem-Cell Transplantation in Older Patients With De Novo Myelodysplastic Syndromes: An International Collaborative Decision Analysis.

    ... were excluded. Transplantation using T-cell depletion or HLA -mismatched or umbilical cord donors was also excluded. RIC ...

    Research Article last updated 07/09/2013 - 3:28pm.

  7. Allogeneic hematopoetic stem cell transplantation in pediatric myelodysplastic syndromes: Improved outcomes for de novo disease.

    ... IPSS score, cytogenetic abnormality, donor type, or HLA match. Larger series are needed to confirm prognostic factors so that ...

    Research Article last updated 10/11/2011 - 5:58pm.

  8. Impact of Azacitidine Before Allogeneic Stem-Cell Transplantation for Myelodysplastic Syndromes: A Study by the Societe Francaise de Greffe de Moelle et de Therapie-Cellulaire and the Groupe-Francophone des Myelodysplasies

    ... recorded in 67 patients. Donors were sibling (n = 75) or HLA -matched unrelated (10/10; n = 88). They received blood (n = 142) or ...

    Research Article last updated 11/05/2012 - 8:57am.

  9. T Cell Depletion for Recipients of HLA Haploidentical Related Donor Stem Cell Grafts (MOHEL)

    For more details on this clinical trial, including contact information, please see this trial’s listing on clinicaltrials.gov: https://clinicaltrials.gov/ct2/show/NCT00368355 ...

    Clinical Trial last updated 04/28/2016 - 12:15pm.

  10. Reduced intensity conditioning, combined transplantation of haploidentical hematopoietic stem cells and mesenchymal stem cells in patients with severe aplastic anemia

    ... of haploidentical HSCs and MSCs on SAA without an HLA -identical sibling donor was safe, effectively reduced the incidence of ...

    Research Article last updated 04/09/2014 - 9:16am.