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  1. Joseph Oved, MD

    ... that have mutations in certain genes (i.e. PIGA and HLA ) which we believe are necessary for the immune system to recognize and ...

    Grant Recipient last updated 06/08/2017 - 10:40am.

  2. Reduced Intensity Conditioning and Haploidentical Related Bone Marrow for Patients With Hematologic Diseases

    ... This is a treatment guideline for HLA -Haploidentical hematopoietic stem cell transplant (HSCT) using ... Must be <75 years old with no 7/8 or 8/8 HLA -matched sibling donor One or more potential related mismatched ...

    Clinical Trial last updated 06/06/2016 - 10:54am.

  3. Stem Cell Transplant from Unrelated Donor in Patients with Severe Aplastic Anemia: Indications, Donor Selection, Conditioning, GVHD Prophylaxis

    ... (HSCT) for patients younger than 40 years, with a HLA identical sibling donor. For patients older than 40 years, IST was the ...

    Research Article last updated 03/03/2015 - 11:27am.

  4. Effect of race on outcomes after allogeneic hematopoietic cell transplantation for severe aplastic anemia.

    ... and Caucasians were matched for age, donor-recipient HLA match, graft type and transplantation year. The median follow-up of ...

    Research Article last updated 10/21/2013 - 11:33am.

  5. Timing of allogeneic stem cell transplantation for myelodysplastic syndromes and aplastic anemia

    ... aplastic anemia , HSCT is a proven cure, but HLA -matched sibling donors are found in fewer than 25% of newly diagnosed ...

    Research Article last updated 03/03/2015 - 1:26pm.

  6. The complex pathophysiology of acquired aplastic anemia

    ... as well as certain human leukocyte antigen ( HLA ) alleles may account for the propensity to immune mediated killing of ...

    Research Article last updated 03/03/2015 - 11:32am.

  7. Timing of allogeneic stem cell transplantation for myelodysplastic syndromes and aplastic anemia

    ... aplastic anemia , HSCT is a proven cure, but HLA -matched sibling donors are found in fewer than 25% of newly diagnosed ...

    Research Article last updated 03/03/2015 - 11:22am.

  8. Bone Marrow Transplantation for Acquired Severe Aplastic Anemia

    ... outcomes similar, though still not identical, to HLA -identical sibling transplants. Recent data on stem cell source, ...

    Research Article last updated 01/20/2015 - 2:47pm.

  9. Hematopoietic stem cell transplantation for aplastic anemia and paroxysmal nocturnal hemoglobinuria: current evidence and recommendations

    ... AA demonstrate cure rates up to 80 and 70% in BMT from HLA -matched siblings and unrelated donor , respectively, with age ...

    Research Article last updated 11/03/2014 - 10:22am.

  10. Good outcome of haploidentical hematopoietic SCT as a salvage therapy in children and adolescents with acquired severe aplastic anemia

    ... refractory to immunosuppressive therapy and lacking HLA -matched related or unrelated donors. Graft failure (GF) and GVHD have ...

    Research Article last updated 09/04/2014 - 11:22am.