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  1. Hematopoietic stem cell transplantation for acquired aplastic anemia

    ... failure of IST, human leukocyte antigen ( HLA )-matched sibling donor BMT is the first-line of treatment for SAA. HLA-matched unrelated donor (URD) BMT is generally recommended for ...

    Research Article last updated 11/01/2016 - 1:55pm.

  2. Bone marrow transplantation versus immunosuppressive therapy in patients with acquired severe aplastic anemia

    ... bone marrow transplantation (BMT), usually from an HLA identical sibling. Whereas long-term survival is comparable with either ... survival (FFS), in patients receiving first-line BMT from an HLA identical sibling, or the first-line IST. Young patients with low ...

    Research Article last updated 07/18/2016 - 10:11am.

  3. Hematopoietic stem cell transplantation for acquired aplastic anemia

    ... failure of IST, human leukocyte antigen ( HLA )-matched sibling donor BMT is the first-line of treatment for SAA. HLA-matched unrelated donor (URD) BMT is generally recommended for ...

    Research Article last updated 10/06/2016 - 9:48am.

  4. Expanded Access Protocol Using CD3+/CD19+ Depleted PBSC (ExpMACs)

    ... is to expand access for patients who lack a fully HLA ( Human leukocyte antigen ) matched sibling donor and who are ... Patients who lack a fully HLA matched sibling and who are candidates for allogeneic hematopoietic ...

    Clinical Trial last updated 06/13/2016 - 1:47pm.

  5. Marrow grafts from HLA-identical siblings for severe aplastic anemia: does limiting the number of transplanted marrow cells reduce the risk of chronic GvHD?

    ... anemia (SAA) underwent marrow transplantation from HLA -identical siblings following a standard conditioning regimen with ...

    Research Article last updated 09/13/2016 - 12:50pm.

  6. Alternative donor transplants for severe aplastic anemia: current experience

    ... (SAA), who lack a human leukocyte antigen ( HLA ) identical sibling donor (SIB), have two therapeutic options: ... or a family mismatched member, in most instances genetically HLA haplo-mismatched (HAPLO). In the present review, we will discuss recent ...

    Research Article last updated 06/07/2016 - 10:52am.

  7. Haploidentical transplantation for pediatric patients with acquired severe aplastic anemia

    ... alternative therapy for pediatric SAA patients without HLA -matched sibling donors. ...

    Research Article last updated 01/24/2017 - 11:52am.

  8. Drug reduces acute GVHD in unrelated HSCTs

    ... myeloablative HSCT was appropriate were paired with 8/8 HLA -A, -B, -C unrelated donors. GVHD prophylaxis consisted of intravenous ...

    Article last updated 02/27/2017 - 1:45pm.

  9. A Comparison of Outcomes for Cord Blood Transplant and Unrelated Bone Marrow Transplant in Adult Aplastic Anemia

    ... To identify differences in outcomes of UCBT and HLA -matched or mismatched unrelated bone marrow transplantation ...

    Research Article last updated 08/15/2016 - 1:06pm.

  10. Biomarkers for predicting clinical response to immunosuppressive therapy in aplastic anemia

    ... the availability of a human leukocyte antigen ( HLA )-matched donor. Although IST is a promising treatment option, the ... choice for AA patients, including up-front HSCT from HLA-matched unrelated donor . The present review summarizes studies ...

    Research Article last updated 06/22/2016 - 10:19am.