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  1. Alternative Donor Transplantation with High-Dose Post-Transplantation Cyclophosphamide for Refractory Severe Aplastic Anemia

    ... allowed for safe expansion of the donor pool to include HLA -haploidentical donors. This approach appears promising in refractory ...

    Research Article last updated 01/24/2017 - 10:04am.

  2. Improved outcome of patients older than 30 years receiving HLA-identical sibling hematopoietic stem cell transplantation for severe acquired aplastic anemia using fludarabine-based conditioning: a comparison with conventional conditioning regimen.

    ... Older age is a limitation for HLA -identical sibling hematopoietic stem cell transplantation (HSCT) as ... impact of age in older patients with SAA receiving an HLA-identical sibling HSCT. Bone Marrow ...

    Research Article last updated 10/11/2011 - 5:58pm.

  3. Resources to Help

    ... Worldwide (BMDW) is the continuing effort to collect the  HLA  phenotypes of volunteer stem cell donors and cord blood units, and is ...

    Topic section last updated 10/20/2017 - 10:23am.

  4. Analysis of allogeneic hematopoietic stem cell transplantation with high-dose cyclophosphamide-induced immune tolerance for severe aplastic anemia

    ... the Beijing Military Region General Hospital. All were HLA mismatched and received CSA; 11 received ATG-intensive immune therapy. ...

    Research Article last updated 11/01/2016 - 1:59pm.

  5. Hematopoietic stem cell transplantation for acquired aplastic anemia

    ... failure of IST, human leukocyte antigen ( HLA )-matched sibling donor BMT is the first-line of treatment for SAA. HLA-matched unrelated donor (URD) BMT is generally recommended for ...

    Research Article last updated 11/01/2016 - 1:55pm.

  6. Diagnosis and treatment of pediatric acquired aplastic anemia (AAA): An initial survey of the North American Pediatric Aplastic Anemia Consortium (NAPAAC)

    ... stem cell transplantation as first line therapy if an HLA -identical sibling is identified; the use of first-line IST containing ... globulin and cyclosporine A (CSA) if an HLA-identical sibling donor is not identified; supportive care ...

    Research Article last updated 12/17/2013 - 8:30am.

  7. Comparison of Outcomes after Transplantation of G-CSF-Stimulated Bone Marrow Grafts versus Bone Marrow or Peripheral Blood Grafts from HLA-Matched Sibling Donors for Patients with Severe Aplastic Anemia.

    ... blood progenitor cells (PBPC) (n = 134) from an HLA -matched sibling. Transplantations occurred in 1997 to 2003. Rates of ... for SAA. Taken together, BM is the preferred graft for HLA-matched sibling transplants for SAA. Bone ...

    Research Article last updated 10/11/2011 - 5:58pm.

  8. Hematopoietic stem cell transplantation for acquired aplastic anemia

    ... failure of IST, human leukocyte antigen ( HLA )-matched sibling donor BMT is the first-line of treatment for SAA. HLA-matched unrelated donor (URD) BMT is generally recommended for ...

    Research Article last updated 10/06/2016 - 9:48am.

  9. A combination of fludarabine, half-dose cyclophosphamide, and anti-thymocyte globulin is an effective conditioning regimen before allogeneic stem cell transplantation for aplastic anemia

    ... chimerism. Two patients who received a graft from an HLA -matched donor subsequently developed mixed chimerism (MC) associated ... However, subsequent MC may be observed, especially after HLA-matched HSCT. Bone Marrow Diseases:  ...

    Research Article last updated 03/06/2014 - 11:00am.

  10. Natural Killer (NK) Cells With HLA Compatible Hematopoietic Transplantation for High Risk Myeloid Malignancies

    ... or blast crisis. Patient must have an identified a HLA (A,B,C,DR) compatible related or unrelated donor who is age 16 ...

    Clinical Trial last updated 06/06/2016 - 1:18pm.