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  1. Selective Depletion of CD45RA+ Naive T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors for Prevention of GVHD

    ... with the principal investigator Patient with a HLA -matched (HLA-A, B, C, and DRB1 molecularly matched) unrelated donor or related ...

    Clinical Trial last updated 06/06/2016 - 2:55pm.

  2. GVHD Prophylaxis With Post Transplant Cyclophosphamide for Patients With Renal Insufficiency Undergoing a Conventional 8/8 HLA-matched Related or Unrelated Donor Allogeneic Hematopoietic Stem Cell Transplant

    ... and myelofibrosis. Patients must have a healthy HLA compatible (8/8 molecularly matched related, or unrelated) donor ...

    Clinical Trial last updated 04/29/2016 - 12:40pm.

  3. Total Marrow Irradiation for Refractory Acute Leukemia

    ... UCB graft will be composed of two partially HLA matched units. Each unit must be matched at 4-6 HLA loci to the recipient and to each other. If two matched units are not ...

    Clinical Trial last updated 05/02/2016 - 9:22am.

  4. 2014 Bone Marrow Failure Disease Symposia - Penn State College of Medicine

    ... with Refractory Aplastic Anemia who lack HLA matched donors Robert  A. Brodsky, MD, Director, Division of ...

    Page last updated 10/29/2014 - 3:39pm.

  5. Clinical Trials Report for February 2015

    ... to respond to immunosuppressive therapy and lack an HLA identical family member, our objectives are to make an initial ...

    Page last updated 01/29/2015 - 10:10am.

  6. Stem Cell Transplants May Be An Option for Some Elderly MDS Patients

    ... if the donor was ≤ 30 years old. Otherwise an HLA -identical donor was preferred.  No prospective studies were available ...

    Research Review last updated 05/02/2016 - 9:33am.

  7. Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow

    ... from parents or legal guardian. Availability of HLA identical or single HLA locus mismatched family donor INCLUSION CRITERIA - Donor: HLA ...

    Clinical Trial last updated 04/28/2016 - 2:08pm.

  8. Transplantation Basics

    ... about genes that we inherit, which determine our tissue ( HLA ) type. We inherit half our genes from our mother and half from the ... one of our siblings has inherited the same combination of HLA genes as we did.  This is an ‘HLA-matched’ sibling -- the most ...

    Interview last updated 04/05/2013 - 2:33pm.

  9. Clinical Trials Report for September 2015

    ... transplantation cyclophosphamide with partially HLA -mismatched donors. This study is being conducted at Sidney Kimmel ...

    Page last updated 08/26/2015 - 1:05pm.

  10. Myeloablative Unrelated Donor Cord Blood Transplantation With T-Cell Depleted Haplo-identical Peripheral Blood Stem Cells for Patients With High Risk Hematological Malignancies

    ... to CB units that have high TNC (> 5.0 x 10^7/kg), good HLA -match (5/6 or 6/6) and are from good quality CB banks a single unit ... Haploidentical donors who are 5/10 or better but not HLA-identical will be used as outlined in section 6.4. Assignment of ...

    Clinical Trial last updated 04/29/2016 - 1:33pm.