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  1. Safety and Efficacy of Patient's Own AD-MSC and AD-HSC Transplantation in Patients With Severe Aplastic Anemia

    ... using an human leukocyte antigen ( HLA ) matched sibling donor, only about 25% of patients have such a donor. ...

    Clinical Trial last updated 04/08/2016 - 11:25pm.

  2. Multicenter Phase II of CD26 Using Sitagliptin for Engraftment After UBC Transplant

    ... there should be no readily available consenting HLA - matched related donor who is either matched fully matched or mismatched at only one locus of HLA-A, -B, and DRB1. No availability of a readily available HLA-matched ...

    Clinical Trial last updated 06/03/2016 - 2:54pm.

  3. Bone Marrow Transplant

    ... a suitable match with the patient's type. This is called HLA matching. A well-matched donor is important to the success of the ...

    Topic section last updated 03/29/2016 - 7:27pm.

  4. Hildegard Greinix, MD

    ... on a large animal model exploring the role of certain HLA antigens in development of bone marrow failure .  The results ...

    Bio last updated 03/11/2016 - 1:41pm.

  5. Calcineurin Inhibitor-Free Interventions for Prevention of Graft-versus-Host Disease (BMT CTN 1301)

    ... be an 8/8 match for human leukocyte antigen ( HLA )-A, -B, and -C at intermediate (or higher) resolution, and -DRB1 at ... for donation1. Unrelated donor must be an 8/8 match at HLA-A, -B, -C and -DRB1 at high resolution using DNA-based typing. Unrelated ...

    Clinical Trial last updated 06/06/2016 - 1:36pm.

  6. Allo HSCT Using RIC for Hematological Diseases

    ... applicable 5/6 or 6/6 related donor match or a 7-8/8 HLA -A,B,C,DRB1 allele matched unrelated donor marrow and/or PBSC ...

    Clinical Trial last updated 05/02/2016 - 9:29am.

  7. Unrelated Donor Stem Cell Transplantation

    ... Greater than one antigen mismatch at HLA -A, B, C or DR plus one allele mismatch at HLA-A, B, C or DR ...

    Clinical Trial last updated 04/28/2016 - 2:16pm.

  8. Clinical Trials Report for April 2016

    ... for patients with human leukocyte antigen ( HLA ) matched unrelated (MUD) and mismatched unrelated (MMUD) donors. ...

    Page last updated 08/10/2016 - 11:00am.

  9. 2014 Bone Marrow Failure Disease Symposia - Penn State College of Medicine

    ... with Refractory Aplastic Anemia who lack HLA matched donors Robert  A. Brodsky, MD, Director, Division of ...

    Page last updated 10/29/2014 - 3:39pm.

  10. Phase I/II MAHCT w/ TCell Depleted Graft w/ Simultaneous Infusion Conventional and Regulatory T Cell

    ... has been excluded Availability of an 6/6 HLA matched sibling defined by Class I (HLA -A and B) serologic typing (or higher resolution) and Class II (HLA-DRB1) ...

    Clinical Trial last updated 05/09/2016 - 3:58pm.