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  1. Calcineurin Inhibitor-Free Interventions for Prevention of Graft-versus-Host Disease (BMT CTN 1301)

    ... be an 8/8 match for human leukocyte antigen ( HLA )-A, -B, and -C at intermediate (or higher) resolution, and -DRB1 at ... for donation1. Unrelated donor must be an 8/8 match at HLA-A, -B, -C and -DRB1 at high resolution using DNA-based typing. Unrelated ...

    Clinical Trial last updated 06/06/2016 - 1:36pm.

  2. Clinical Trials Report for April 2016

    ... for patients with human leukocyte antigen ( HLA ) matched unrelated (MUD) and mismatched unrelated (MMUD) donors. ...

    Page last updated 08/10/2016 - 11:00am.

  3. Bone Marrow Transplant

    ... a suitable match with the patient's type. This is called HLA matching. A well-matched donor is important to the success of the ...

    Topic section last updated 03/29/2016 - 7:27pm.

  4. Hildegard Greinix, MD

    ... on a large animal model exploring the role of certain HLA antigens in development of bone marrow failure .  The results ...

    Bio last updated 03/11/2016 - 1:41pm.

  5. Allo HSCT Using RIC for Hematological Diseases

    ... applicable 5/6 or 6/6 related donor match or a 7-8/8 HLA -A,B,C,DRB1 allele matched unrelated donor marrow and/or PBSC ...

    Clinical Trial last updated 05/02/2016 - 9:29am.

  6. Unrelated Donor Stem Cell Transplantation

    ... Greater than one antigen mismatch at HLA -A, B, C or DR plus one allele mismatch at HLA-A, B, C or DR ...

    Clinical Trial last updated 04/28/2016 - 2:16pm.

  7. Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203)

    ... as follows: Sibling donor must be a 6/6 match for HLA -A and -B at intermediate (or higher) resolution, and -DRB1 at high ... Unrelated donor must be a 7/8 or 8/8 match at HLA-A, -B, -C and -DRB1 at high resolution using DNA-based typing. Unrelated ...

    Clinical Trial last updated 06/06/2016 - 1:59pm.

  8. Phase I/II MAHCT w/ TCell Depleted Graft w/ Simultaneous Infusion Conventional and Regulatory T Cell

    ... has been excluded Availability of an 6/6 HLA matched sibling defined by Class I (HLA -A and B) serologic typing (or higher resolution) and Class II (HLA-DRB1) ...

    Clinical Trial last updated 05/09/2016 - 3:58pm.

  9. HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy (RAFA)

    ... Donors will be either human leukocyte antigen ( HLA ) compatible unrelated or HLA-genotypically matched related donors (no fully matched sibling donor). ...

    Clinical Trial last updated 05/09/2016 - 3:19pm.

  10. Allogeneic Bone Marrow Transplantation Using Less Intensive Therapy

    ... eligible. Patient's < or = 75 years who have a 7-8/8 HLA -A,B,C,DRB1 allele matched unrelated volunteer marrow and/or peripheral ...

    Clinical Trial last updated 05/02/2016 - 2:20pm.