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  1. Unrelated Donor Stem Cell Transplantation

    ... Greater than one antigen mismatch at HLA -A, B, C or DR plus one allele mismatch at HLA-A, B, C or DR Intervention:  ...

    Clinical Trial last updated 04/28/2016 - 2:16pm.

  2. Hildegard Greinix, MD

    ... on a large animal model exploring the role of certain HLA antigens in development of bone marrow failure .  The results ...

    Bio last updated 03/11/2016 - 1:41pm.

  3. Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203)

    ... as follows: Sibling donor must be a 6/6 match for HLA -A and -B at intermediate (or higher) resolution, and -DRB1 at high ... Unrelated donor must be a 7/8 or 8/8 match at HLA-A, -B, -C and -DRB1 at high resolution using DNA-based typing. Unrelated ...

    Clinical Trial last updated 06/06/2016 - 1:59pm.

  4. Phase I/II MAHCT w/ TCell Depleted Graft w/ Simultaneous Infusion Conventional and Regulatory T Cell

    ... has been excluded Availability of an 6/6 HLA matched sibling defined by Class I (HLA -A and B) serologic typing (or higher resolution) and Class II (HLA-DRB1) ...

    Clinical Trial last updated 05/09/2016 - 3:58pm.

  5. HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy (RAFA)

    ... Donors will be either human leukocyte antigen ( HLA ) compatible unrelated or HLA-genotypically matched related donors (no fully matched sibling donor). ...

    Clinical Trial last updated 05/09/2016 - 3:19pm.

  6. Allogeneic Stem Cell Transplant With Alpha/Beta T AND B Cell Depletion for Hematologic Malignancies (AB-CliniMACs)

    ... to one antigen/one antigen and one allele or a related, HLA match other than a sibling. Intervention:  ...

    Clinical Trial last updated 06/06/2016 - 3:10pm.

  7. Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts for the Prevention of GVHD in Children

    ... Patient with a human leukocyte antigen ( HLA )-identical (HLA-A, B, C, and ribonucleic acid [RNA] binding motif protein 45 [DRB1] ...

    Clinical Trial last updated 06/13/2016 - 2:29pm.

  8. Allogeneic Stem Cell Transplant With Alpha/Beta T AND B Cell Depletion for Hematologic Malignancies (AB-CliniMACs)

    ... to one antigen/one antigen and one allele or a related, HLA match other than a sibling. Intervention:  ...

    Clinical Trial last updated 06/03/2016 - 2:45pm.

  9. Allogeneic Bone Marrow Transplantation Using Less Intensive Therapy

    ... eligible. Patient's < or = 75 years who have a 7-8/8 HLA -A,B,C,DRB1 allele matched unrelated volunteer marrow and/or peripheral ...

    Clinical Trial last updated 05/02/2016 - 2:20pm.

  10. CD8+ Memory T-Cells as Consolidative Therapy After Donor Non-myeloablative Hematopoietic Cell Transplant in Treating Patients With Leukemia or Lymphoma

    ... Must have a human leukocyte antigen ( HLA )-matched or single allele-mismatched adult sibling serving as donor ... consent to participate in the trial DONOR: Must be an HLA-matched or single allele mismatched sibling of enrolled transplant patient ...

    Clinical Trial last updated 04/29/2016 - 12:36pm.